Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.1.258: 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase

This is an abbreviated version!
For detailed information about 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase, go to the full flat file.

Reaction

a [methyl-Co(III) corrinoid Fe-S protein]
+
tetrahydrofolate
=
a [Co(I) corrinoid Fe-S protein]
+
5-methyltetrahydrofolate

Synonyms

acsE, methyltetrahydrofo1ate:corrinoid/iron-sulfur protein methyltransferase, methyltetrahydrofolate corrinoid-iron sulfur protein methyltransferase, methyltetrahydrofolate, corrinoid iron–sulfur protein methyltransferase, methyltetrahydrofolate- and corrinoid-dependent methyltransferase, methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase, methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase MeTr, MeTr

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.258 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase

Substrates Products

Substrates Products on EC 2.1.1.258 - 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
cobalamin + 5-methyltetrahydrofolate
methylcobalamin + tetrahydrofolate
show the reaction diagram
hydroxocobalamin + 5-methyltetrahydrofolate
methylcobalamin + tetrahydrofolate
show the reaction diagram
-
-
-
-
r
hydroxycobalamin + 5-methyltetrahydrofolate
methylcobalamin + tetrahydrofolate
show the reaction diagram
methylcobalamin + tetrahydrofolate
?
show the reaction diagram
-
-
-
?
methylcobalamin + tetrahydrofolate
hydroxocobalamin + 5-methyltetrahydrofolate
show the reaction diagram
[Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate
[methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate
show the reaction diagram
[methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate
[Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate
show the reaction diagram
-
-
-
-
r
additional information
?
-
-
only the protonated enzyme form is active
-
-
?