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2.1.1.251: methylated-thiol-coenzyme M methyltransferase

This is an abbreviated version!
For detailed information about methylated-thiol-coenzyme M methyltransferase, go to the full flat file.

Reaction

a [methyl-Co(III) methylated-thiol-specific corrinoid protein]
+
CoM
=
methyl-CoM
+
a [Co(I) methylated-thiol-specific corrinoid protein]

Synonyms

480-kDa CoM methylase, CoM methylase, DMS:CoM methyltransferase, methylthiol:coenzyme M methyltransferase, methylthiol:CoM methyltransferase, methyltransferase II, MMPA:CoM methyltransferase, MtsA

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.251 methylated-thiol-coenzyme M methyltransferase

Cloned

Cloned on EC 2.1.1.251 - methylated-thiol-coenzyme M methyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene mtsA, DNA and amino acid sequence determination and analysis, expression in Escherichia coli strain DH5alpha. The gene encoding the alpha subunit of the CoM methylase, mtsA, is 5' to the gene encoding the beta subunit, mtsB, regulated cotranscription of mtsA and mtsB
gene mtsA, functional expression in Escherichia coli strain BL21(DE3)pLysS, MtsA is expressed largely in an insoluble form
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