2.1.1.249: dimethylamine-corrinoid protein Co-methyltransferase

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For detailed information about dimethylamine-corrinoid protein Co-methyltransferase, go to the full flat file.

Reaction

Synonyms

dimethyl-12-HBI methyltransferase, dimethylamine methyltransferase, dimethylamine/5-hydroxybenzimidazolylcobamide methyltransferase, dimethylamine: corrinoid methyltransferase, dimethylamine:CoM methyltransferase, dimethylamine:corrinoid methyltransferase, DMA methyltransferase, DMA-MT, DMA:CoM methyltransferase, DMA:corrinoid methyltransferase, MtbB, MtbB1, MtbB2, MtbB3, MtcB

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.249 dimethylamine-corrinoid protein Co-methyltransferase

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Results	in table
7	Activating Compound
277	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
2	Cofactor
16	General Information
2	Inhibitors
1	Ki Value [mM]
3	Metals/Ions
8	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
27	Organism
3	Pathway
3	pH Optimum
1	pI Value
5	Purification (Commentary)
3	Reaction
15	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
22	Substrates and Products (Substrate)
8	Subunits
34	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]

Purification

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Purification on EC 2.1.1.249 - dimethylamine-corrinoid protein Co-methyltransferase

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

Methanosarcina barkeri

O93661

727831

native enzyme 35.2fold MtbB1 by two steps of anion exchange chromatography, and adsorption and hydrophobic interaction chromatography

Methanosarcina barkeri

-

680470

native enzyme 62.8fold by ammonium sulfate fractionation, hydrophobic interaction chromatography, ultrafiltration, and anion exchange chromatography

Methanosarcina barkeri

-

717558

native enzyme by three different steps of anion exchange chromatography, adsorption and hydrophobic interaction chromatography

Methanosarcina barkeri

Q9P9N0

717771

native enzyme to homogeneity

Methanosarcina barkeri

-

717560