2.1.1.234: dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

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For detailed information about dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, go to the full flat file.

Reaction

2 S-adenosyl-L-methionine +

dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose

= 2 S-adenosyl-L-homocysteine +

dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose

Synonyms

DesVI

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.234 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

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Results	in table
252	AA Sequence
3	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
1	General Information
1	General Stability
2	kcat/KM [mM/s]
2	KM Value [mM]
3	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
3	Organism
6	Pathway
2	pH Optimum
3	Purification (Commentary)
1	Reaction
3	Reference
7	Substrates and Products (Substrate)
4	Subunits
3	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Turnover Number [1/s]

Reference

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Reference on EC 2.1.1.234 - dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

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713755

Chang, C.w.; Zhao, L.; Yamase, H., Liu, H.w.

DesVI: A new member of the sugar N,N-dimethyltransferase family involved in the biosynthesis of desosamine

Angew. Chem. Int. Ed. Engl.

2160-2163

2000

Streptomyces venezuelae (Q9ZGH6)

10941048

714149

Chen, H.; Yamase, H.; Murakami, K.; Chang, C.W.; Zhao, L.; Zhao, Z.; Liu, H.W.

Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine

Biochemistry

9165-9183

2002

Streptomyces venezuelae (Q9ZGH6)

12119032

714167

Burgie, E.S.; Holden, H.M.

Three-dimensional structure of DesVI from Streptomyces venezuelae: a sugar N,N-dimethyltransferase required for dTDP-desosamine biosynthesis

Biochemistry

3982-3988

2008

Streptomyces venezuelae (Q9ZGH6), Streptomyces venezuelae

18327916