2.1.1.230: 23S rRNA (adenosine1067-2'-O)-methyltransferase This is an abbreviated version! For detailed information about 23S rRNA (adenosine1067-2'-O)-methyltransferase, go to the full flat file .
Reaction
S-adenosyl-L-methionine +
adenosine1067 in 23S rRNA =
S-adenosyl-L-homocysteine +
2'-O-methyladenosine1067 in 23S rRNA
Synonyms EC 2.1.1.66, NHR, NHR protein, nosiheptide resistance methyltransferase, nosiheptide-resistance methyltransferase, thiostrepton resistance methyltransferase, thiostrepton-resistance methylase, thiostrepton-resistance methyltransferase, TSR
ECTree
Systematic Name
Systematic Name on EC 2.1.1.230 - 23S rRNA (adenosine1067-2'-O)-methyltransferase
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S-adenosyl-L-methionine:23S rRNA (adenosine1067-2'-O)-methyltransferase
The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton [2].