2.1.1.228: tRNA (guanine37-N1)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanine37-N1)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.228

2.1.1.228

methyltransferases

anticodon

adomet

1-methylguanosine

drug development

n2-guanine

trmt10a

1-methyladenine

adomet-dependent

5-methyluridine

trmfo

n1-methylation

methyl-deficient

7-methylguanine

spout

epitranscriptome

nsun2-mediated

medicine

Reaction

Synonyms

At3g56120, aTrm5a methyltransferase, aTrm5a/Taw22-like enzyme, AtTrm5a, bacterial tRNA (guanine37-N1)-methyltransferase, bacterial tRNA-(N1G37) methyltransferase, EC 2.1.1.31, EcTrmD, HiTrmD, HsTrm5, m1G37 tRNA methyltransferase, m1G37-forming tRNA methyltransferase, Mj-Trm5, MJ0883, MjTrm5, MjTrm5b, mono-functional methyltransferase, More, MtbTrmD, NEQ228, PA14_15990, PAB2272, PAB_RS03940, PaTrm5a, PaTrm5b, PaTrmD, SaTrmD, Ta0997, TAW22, transfer RNA (m1G37) methyltransferase, Trm1, TRM5, Trm5a, Trm5a/Taw22-like enzyme, trm5b, Trm5p, TrmD, TRMT5, tRNA (guanine(37)-N1)-methyltransferase 1, tRNA (guanine37-N1)-methyltransferase, tRNA (guanosine-1) methyltransferase, tRNA (m1G37) methyltransferase, tRNA (m1G37)-methyltransferase, tRNA m1G37 methyltransferase, tRNA methyltransferase, tRNA methyltransferase 5, tRNA methyltransferase D, tRNA(m(1)G37)methyltransferase, tRNA(m1G37) methyltransferase, tRNA(m1G37) MTase, tRNA(m1G37)methyltransferase, tRNA-(N1G37) methyltransferase, tRNAPhe:imG2 methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.228 tRNA (guanine37-N1)-methyltransferase

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Results	in table
1	Activating Compound
43500	AA Sequence
16	Application
31	Cloned(Commentary)
49	Cofactor
17	Crystallization (Commentary)
98	Disease/ Diagnostics
3	Expression
219	General Information
3	General Stability
89	IC50 Value
190	Inhibitors
40	kcat/KM [mM/s]
27	Ki Value [mM]
91	KM Value [mM]
8	Localization
44	Metals/Ions
8	Molecular Weight [Da]
116	Natural Substrates/ Products (Substrates)
168	Organism
3	Pathway
201	PDB ID
29	pH Optimum
5	pH Range
126	Protein Variants
23	Purification (Commentary)
9	Reaction
103	Reference
3	Source Tissue
269	Substrates and Products (Substrate)
58	Subunits
226	Synonyms
1	Systematic Name
28	Temperature Optimum [°C]
3	Temperature Stability [°C]
43	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 2.1.1.228 - tRNA (guanine37-N1)-methyltransferase

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6.1

guanine37 in Escherichia coli tRNAPro

Escherichia coli

pH 8.0, 37°C

712739

36.9

guanine37 in Methanocaldococcus jannaschii tRNA(Cys)

Methanocaldococcus jannaschii

Q58293

pH 8.0, 50°C

701123

0.017 - 11.9

guanine37 in Methanocaldococcus jannaschii tRNACys

9 entries

1.7 - 7.22

guanine37 in Methanocaldococcus jannaschii tRNAPro

2 entries

guanine37 in tRNAArg

Haemophilus influenzae

pH 8.0, temperature not specified in the publication

737174

guanine37 in tRNACys

Homo sapiens

Q32P41

recombinant enzyme, pH 7.3, 37°C

737226

0.000078 - 280

guanine37 in tRNAGlnCUG

4 entries

130

guanine37 in tRNAGlnG36A

Haemophilus influenzae

pH 8.0, temperature not specified in the publication

737174

guanine37 in tRNAGlnG36C

Haemophilus influenzae

pH 8.0, temperature not specified in the publication

737174

guanine37 in tRNAGlnG36U

Haemophilus influenzae

pH 8.0, temperature not specified in the publication

737174

0.024 - 40

guanine37 in tRNALeu

7 entries

9.44

guanine37 in tRNALeu(CAG)

Pseudomonas aeruginosa

Q02RL6

pH and temperature not specified in the publication

755697

357

guanine37 in tRNALeu(GAC)

Streptococcus pneumoniae

pH 8.5, 37°C

662010

270.8

guanine37 in tRNALeu(GAG)

Pseudomonas aeruginosa

Q02RL6

pH 7.5, 37°C, recombinant enzyme

758329

130

guanine37 in tRNAPro

Haemophilus influenzae

pH 8.0, temperature not specified in the publication

737174

S-adenosyl-L-homocysteine

Streptococcus pneumoniae

pH 8.5, 37°C

662010

0.2 - 72.2

S-adenosyl-L-methionine

4 entries

additional information

2 entries