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2.1.1.222: 2-polyprenyl-6-hydroxyphenol methylase

This is an abbreviated version!
For detailed information about 2-polyprenyl-6-hydroxyphenol methylase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
3-(all-trans-polyprenyl)benzene-1,2-diol
=
S-adenosyl-L-homocysteine
+
2-methoxy-6-(all-trans-polyprenyl)phenol

Synonyms

2-polyprenyl-6-hydroxyphenyl methylase, 3-demethyl ubiquinone-9 3-methyltransferase, UbiG, UbiG methyltransferase, ubiquinone biosynthesis O-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.222 2-polyprenyl-6-hydroxyphenol methylase

Reference

Reference on EC 2.1.1.222 - 2-polyprenyl-6-hydroxyphenol methylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Poon, W.W.; Barkovich, R.J.; Hsu, A.Y.; Frankel, A.; Lee, P.T.; Sheperd, J.N.; Myles, D.C.; Clarke, C.F.
Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis
J. Biol. Chem.
274
21665-21672
1999
Escherichia coli, Saccharomyces cerevisiae (P27680), Rattus norvegicus (Q63159)
Manually annotated by BRENDA team
Jonassen, T.; Clarke, C.F.
Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis
J. Biol. Chem.
275
12381-12387
2000
Homo sapiens (Q9NZJ6)
Manually annotated by BRENDA team
Hsu, A.Y.; Poon, W.W.; Shepherd, J.A.; Myles, D.C.; Clarke, C.F.
Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis
Biochemistry
35
9797-9806
1996
Escherichia coli
Manually annotated by BRENDA team
Gibert, I.; Llagostera, M.; Barbe, J.
Regulation of ubiG gene expression in Escherichia coli
J. Bacteriol.
170
1346-1349
1988
Escherichia coli
Manually annotated by BRENDA team
Joyce, A.R.
Reed, J.L.; White, A.; Edwards, R.; Osterman, A.; Baba, T.; Mori, H.; Lesely, S.A.; Palsson, B.; Agarwalla, S.: Experimental and computational assessment of conditionally essential genes in Escherichia coli
J. Bacteriol.
188
8259-8271
2006
Escherichia coli
Manually annotated by BRENDA team
Soballe, B.; Poole, R.K.
Ubiquinone limits oxidative stress in Escherichia coli
Microbiology
146
787-796
2000
Escherichia coli
Manually annotated by BRENDA team
Xing, L.; Zhu, Y.; Fang, P.; Wang, J.; Zeng, F.; Li, X.; Teng, M.; Li, X.
Crystallization and preliminary crystallographic studies of UbiG, an O-methyltransferase from Escherichia coli
Acta Crystallogr. Sect. F
67
727-729
2011
Escherichia coli
Manually annotated by BRENDA team
Gonidakis, S.; Finkel, S.E.; Longo, V.D.
Lifespan extension and paraquat resistance in a ubiquinone-deficient Escherichia coli mutant depend on transcription factors ArcA and TdcA
Aging
3
291-303
2011
Escherichia coli, Escherichia coli BW25113
Manually annotated by BRENDA team
Lu, W.; Shi, Y.; He, S.; Fei, Y.; Yu, K.; Yu, H.
Enhanced production of CoQ10 by constitutive overexpression of 3-demethyl ubiquinone-9 3-methyltransferase under tac promoter in Rhodobacter sphaeroides
Biochem. Eng. J.
72
42-47
2013
Cereibacter sphaeroides (Q3IYM5)
Manually annotated by BRENDA team
Zhu, Y.; Wu, B.; Zhang, X.; Fan, X.; Niu, L.; Li, X.; Wang, J.; Teng, M.
Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins
Biochem. J.
470
105-114
2015
Escherichia coli (P17993)
Manually annotated by BRENDA team
Lu, W.; Ye, L.; Lv, X.; Xie, W.; Gu, J.; Chen, Z.; Zhu, Y.; Li, A.; Yu, H.
Identification and elimination of metabolic bottlenecks in the quinone modification pathway for enhanced coenzyme Q10 production in Rhodobacter sphaeroides
Metab. Eng.
29
208-216
2015
Cereibacter sphaeroides
Manually annotated by BRENDA team
Zhu, Y.; Jiang, X.; Wang, C.; Liu, Y.; Fan, X.; Zhang, L.; Niu, L.; Teng, M.; Li, X.
Structural insights into the methyl donor recognition model of a novel membrane-binding protein UbiG
Sci. Rep.
6
23147
2016
Escherichia coli (C3T302)
Manually annotated by BRENDA team