2.1.1.222: 2-polyprenyl-6-hydroxyphenol methylase

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For detailed information about 2-polyprenyl-6-hydroxyphenol methylase, go to the full flat file.

Reaction

3-(all-trans-polyprenyl)benzene-1,2-diol

2-methoxy-6-(all-trans-polyprenyl)phenol

Synonyms

2-polyprenyl-6-hydroxyphenyl methylase, 3-demethyl ubiquinone-9 3-methyltransferase, UbiG, UbiG methyltransferase, ubiquinone biosynthesis O-methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.222 2-polyprenyl-6-hydroxyphenol methylase

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Results	in table
15197	AA Sequence
6	Cloned(Commentary)
2	Cofactor
3	Crystallization (Commentary)
2	Expression
6	General Information
5	Localization
2	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
48	Organism
9	Pathway
3	PDB ID
3	pH Optimum
12	Protein Variants
3	Purification (Commentary)
1	Reaction
15	Reference
1	Source Tissue
16	Substrates and Products (Substrate)
3	Subunits
14	Synonyms
1	Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.222 - 2-polyprenyl-6-hydroxyphenol methylase

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S-adenosyl-L-methionine + 3-(all-trans-octaprenyl)benzene-1,2-diol

S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-octaprenyl)phenol

Escherichia coli

the enzyme catalyzes two methylation steps in the biosynthesis of ubiquinone-8 in Escherichia coli, 1. the methylation of 3-(all-trans-octaprenyl)benzene-1,2-diol and 2. the methylation of 3-demethylubiquinol-8 (this reaction is classified as EC 2.1.1.64)

485140, 702193

additional information

3 entries