2.1.1.214: tRNA (guanine10-N2)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanine10-N2)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.214

2.1.1.214

methyltransferases

nucleoside

mtases

anticodons

1-methyladenosine

s-adenosylmethionine-dependent

methylase

zinc-finger

two-subunit

archaeon

rrna

decoding

zinc-binding

Reaction

Synonyms

(m2G10) methyltransferase, archaeal Trm11, EC 2.1.1.32, eukaryotic m2G10 tRNA methyltransferase, eukaryotic Trm11, N2, N2-dimethylguanosine tRNA methyltransferase, N2,N2-dimethylguanosine tRNA methyltransferase, Tk0981, Trm-G10, Trm-m22G10, Trm11, Trm11-Trm112 complex, Trm11p, Trmp112p, tRNA m2G10/m22G10 methyltransferase, tRNA MTase, YOL124c

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.214 tRNA (guanine10-N2)-methyltransferase

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Results	in table
1	Activating Compound
19	AA Sequence
4	Cloned(Commentary)
4	Cofactor
16	General Information
1	Inhibitors
1	KM Value [mM]
1	Localization
4	Metals/Ions
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
8	Organism
1	Pathway
2	pH Optimum
4	Protein Variants
2	Purification (Commentary)
1	Reaction
8	Reference
3	Source Tissue
13	Substrates and Products (Substrate)
5	Subunits
33	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

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Reference on EC 2.1.1.214 - tRNA (guanine10-N2)-methyltransferase

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675961

Purushothaman, S.K.; Bujnicki, J.M.; Grosjean, H.; Lapeyre, B.

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA

Mol. Cell. Biol.

4359-4370

2005

Saccharomyces cerevisiae (Q12463), Saccharomyces cerevisiae

15899842

705993

Okada, K.; Muneyoshi, Y.; Endo, Y.; Hori, H.

Production of yeast (m2G10) methyltransferase (Trm11 and Trm112 complex) in a wheat germ cell-free translation system

Nucleic Acids Symp. Ser.

303-304

2009

Saccharomyces cerevisiae (Q12463), Saccharomyces cerevisiae

19749381

712436

Mazauric, M.H.; Dirick, L.; Purushothaman, S.K.; Bj�rk, G.R.; Lapeyre, B.

Trm112p is a 15-kDa zinc finger protein essential for the activity of two tRNA and one protein methyltransferases in yeast

J. Biol. Chem.

285

18505-18515

2010

Saccharomyces cerevisiae

20400505

757106

Hirata, A.; Suzuki, T.; Nagano, T.; Fujii, D.; Okamoto, M.; Sora, M.; Lowe, T.M.; Kanai, T.; Atomi, H.; Suzuki, T.; Hori, H.

Distinct modified nucleosides in tRNATrp from thehyperthermophilic archaeon Thermococcus kodakarensis and requirement of tRNA m2G10/m22G10 methyltransferase (archaeal Trm11) for survival at high temperatures

J. Bacteriol.

201

e00448-19

2019

Thermococcus kodakarensis (Q5JID5), Thermococcus kodakarensis, Thermococcus kodakarensis JCM 12380 (Q5JID5), Thermococcus kodakarensis ATCC BAA-918 (Q5JID5)

31405913

757844

Bourgeois, G.; Marcoux, J.; Saliou, J.M.; Cianferani, S.; Graille, M.

Activation mode of the eukaryotic m2G10 tRNA methyltransferase Trm11 by its partner protein Trm112

Nucleic Acids Res.

1971-1982

2017

Saccharomyces cerevisiae (Q12463), Saccharomyces cerevisiae ATCC 204508 (Q12463)

27986851