2.1.1.212: 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase

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For detailed information about 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase, go to the full flat file.

Reaction

Synonyms

2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase/isoflavone 4'-O-methyltransferase, 2-hydroxyisoflavanone 4'-O-methyltransferase, HI4'OMT, HI4'OMT/HM3OMT, HI4OMT, HMM1, More, MtIOMT5, S-adenosyl-L-methionine: 2-hydroxyisoflavanone 4'-O-methyltransferase, SAM: 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase, SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.212 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase

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6	AA Sequence
6	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
3	General Information
1	kcat/KM [mM/s]
4	KM Value [mM]
10	Natural Substrates/ Products (Substrates)
11	Organism
2	Pathway
2	pH Optimum
2	Purification (Commentary)
1	Reaction
11	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
21	Substrates and Products (Substrate)
15	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.1.1.212 - 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase

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S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase

Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position. No activity with isoflavones [2]. The enzyme is involved in formononetin biosynthesis in legumes [1]. The protein from pea (Pisum sativum) also methylates (+)-6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270, (+)-6a-hydroxymaackiain 3-O-methyltransferase) [4].