2.1.1.21: methylamine-glutamate N-methyltransferase

This is an abbreviated version!
For detailed information about methylamine-glutamate N-methyltransferase, go to the full flat file.

Reaction

Synonyms

methylamine-glutamate methyltransferase, N-methylglutamate synthase, N-methylglutamate synthetase, NMGS

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.21 methylamine-glutamate N-methyltransferase

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Results	in table
40	AA Sequence
1	CAS Registry Number
6	Cofactor
8	Inhibitors
1	Ki Value [mM]
2	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
16	Organism
6	Pathway
2	pH Optimum
1	pH Range
3	Purification (Commentary)
1	Reaction
4	Reaction Type
9	Reference
10	Specific Activity [micromol/min/mg]
30	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Reference

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Reference on EC 2.1.1.21 - methylamine-glutamate N-methyltransferase

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485233

Shaw, W.V.; Tsai, L.; Stadtman, E.R.

The enzymatic synthesis of N-methylglutamic acid

J. Biol. Chem.

241

935-945

1966

Pseudomonas sp., Pseudomonas sp. AM1(2006)

5905132

485234

Pollock, R.J.; Hersh, L.B.

N-Methylglutamate synthetase. The use of flavin mononucleotide in oxidative catalysis

J. Biol. Chem.

248

6724-6733

1973

Pseudomonas sp.

4745441

485235

Schuman Jorns, M.; Hersh, L.B.

N-Methylglutamate synthetase. Substrate-flavin hydrogen transfer reactions probed with deazaflavin mononucleotide

J. Biol. Chem.

250

3620-3628

1975

Pseudomonas sp., Pseudomonas sp. AM1(2006)

1126928

485236

Hersh, L.B.

N-Methyl-L-glutamate synthase

Methods Enzymol.

113

36-42

1985

Pseudomonas sp.

3911004

485237

Bornemann, S.

Flavoenzymes that catalyse reactions with no net redox change

Nat. Prod. Rep.

761-772

2002

Pseudomonas sp.

12521268

700286

Latypova, E.; Yang, S.; Wang, Y.S.; Wang, T.; Chavkin, T.A.; Hackett, M.; Schaefer, H.; Kalyuzhnaya, M.G.

Genetics of the glutamate-mediated methylamine utilization pathway in the facultative methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5

Mol. Microbiol.

426-439

2010

Methyloversatilis universalis, Methyloversatilis universalis FAM5

19943898