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2.1.1.205: tRNA (cytidine32/guanosine34-2'-O)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (cytidine32/guanosine34-2'-O)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
cytidine32/guanosine34 in tRNA
=
S-adenosyl-L-homocysteine
+
2'-O-methylcytidine32/2'-O-methylguanosine34 in tRNA

Synonyms

trm7, Trm7p

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.205 tRNA (cytidine32/guanosine34-2'-O)-methyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.1.1.205 - tRNA (cytidine32/guanosine34-2'-O)-methyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNA
S-adenosyl-L-homocysteine + 2'-O-methylcytidine32/2'-O-methylguanosine34 in tRNA
show the reaction diagram
the enzyme catalyses the formation of 2'-O-methylnucleotides at positions 32 and 34 of the yeast tRNAPhe, tRNATrp and, possibly, tRNALeu
-
-
?
S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNALeu
S-adenosyl-L-homocysteine + 2'-O-methylcytidine32/2'-O methylguanosine34 in tRNALeu
show the reaction diagram
S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNAPhe
S-adenosyl-L-homocysteine + 2'-O-methylcytidine32/2'-O methylguanosine34 in tRNAPhe
show the reaction diagram
S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNATrp
S-adenosyl-L-homocysteine + 2'-O-methylcytidine32/2'-O methylguanosine34 in tRNATrp
show the reaction diagram