2.1.1.2: guanidinoacetate N-methyltransferase

This is an abbreviated version!
For detailed information about guanidinoacetate N-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.2

2.1.1.2

creatine

amidinotransferase

epilepsy

inborn

arginine:glycine

treatable

gamt-deficient

phosphocreatine

extrapyramidal

slc6a8

neurometabolic

medicine

autistic-like

analysis

Reaction

Synonyms

GA methylpherase, GAA methyltransferase, GAMT, guanidinoacetate methyltransferase, guanidinoacetate N-methyltransferase, guanidinoacetate transmethylase, guanidoacetate methyltransferase, methionine-guanidinoacetic transmethylase, MIM 601240, N-guanidinoacetate methyltransferase, S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.2 guanidinoacetate N-methyltransferase

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Results	in table
17	Activating Compound
368	AA Sequence
7	Application
1	CAS Registry Number
8	Cloned(Commentary)
4	Cofactor
3	Crystallization (Commentary)
324	Disease/ Diagnostics
6	Expression
7	General Information
1	General Stability
20	Inhibitors
5	Ki Value [mM]
22	KM Value [mM]
2	Localization
4	Metals/Ions
8	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
44	Organism
6	Pathway
16	PDB ID
6	pH Optimum
41	Protein Variants
5	Purification (Commentary)
4	Reaction
6	Reaction Type
43	Reference
114	Source Tissue
19	Specific Activity [micromol/min/mg]
3	Storage Stability
38	Substrates and Products (Substrate)
3	Subunits
46	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
8	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.2 - guanidinoacetate N-methyltransferase

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S-adenosyl-L-methionine + guanidinoacetate

S-adenosyl-L-homocysteine + creatine

18 entries

additional information

Mus musculus

together with creatine/phosphocreatine shuttle system involved in brain energy homeostasis through a neuron-glial relationship

661657