2.1.1.189: 23S rRNA (uracil747-C5)-methyltransferase
This is an abbreviated version!
For detailed information about 23S rRNA (uracil747-C5)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.189
-
2.1.1.189
-
rrnas
-
pneumoniae
-
archaea
-
paralogues
-
renamed
-
eukaryota
-
in-vitro
-
s-adenosylmethionine
-
thermococcales
-
archetypical
-
pyrococcus
-
methyltransferases
-
5-methyl
- 2.1.1.189
- rrnas
- pneumoniae
- archaea
- paralogues
-
renamed
- eukaryota
-
in-vitro
- s-adenosylmethionine
- thermococcales
-
archetypical
-
pyrococcus
- methyltransferases
-
5-methyl
Reaction
Synonyms
m5U methyltransferase, PAB0760, RlmC, RlmCD, RNA uridine methyltransferase B, RumB, SP 1029, SP_1029, YbjF, YefA
ECTree
Advanced search results
Substrates Products
Substrates Products on EC 2.1.1.189 - 23S rRNA (uracil747-C5)-methyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
S-adenosyl-L-methionine + 5'-740GGCACGUUGAAAAGUGCC757-3'
S-adenosyl-L-homocysteine + 5'-740GGCACGUm5UGAAAAGUGCC757-3'
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5'-740GGCACGUm5UGAAAAGUGCC757-3'
18-mer RNA analogue of the 23S rRNA helix 35
-
-
?
S-adenosyl-L-methionine + 5'-740GGCACGUUGAAAAGUGCC757-3'
S-adenosyl-L-homocysteine + 5'-740GGCACGUm5UGAAAAGUGCC757-3'
18-mer RNA analogue of the 23S rRNA helix 35
-
-
?
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
-
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
it is not possible to generate a recombinant version of YbjF that retains in vitro activity, so the function of this enzyme is defined in vivo by engineering a ybjF knockout strain
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
RlmC recognizes a specific uridine within the loop of 23S rRNA hairpin 35
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
-
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
PAB0760 is a m5U methyltransferase and recognizes a specific uridine within the loop of 23S rRNA hairpin 35 in a highly specific manner
product identification by reverse transcriptase primer extension and MALDI mass spectrometry
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
-
-
-
?
S-adenosyl-L-methionine + uracil747 in 23S rRNA
S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA
-
-
-
-
?
?
-
methylation of U747 and U1939 in Bacillus subtilis rRNA is catalysed by a single enzyme, YefA, MALDI mass spectrometry product identification. YefA is not involved in tRNA methylation, or in 23S rRNA m554 methylation
-
-
?
additional information
?
-
-
methylation of U747 and U1939 in Bacillus subtilis rRNA is catalysed by a single enzyme, YefA, MALDI mass spectrometry product identification. YefA is not involved in tRNA methylation, or in 23S rRNA m554 methylation
-
-
?
additional information
?
-
methylation of U747 and U1939 in Bacillus subtilis rRNA is catalysed by a single enzyme, YefA, MALDI mass spectrometry product identification. YefA is not involved in tRNA methylation, or in 23S rRNA m554 methylation
-
-
?
additional information
?
-
-
the enzyme also methylates uracil1939 in 23S rRNA
-
-
?
additional information
?
-
enzyme introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.18189 and 2.11.190
-
-
-
additional information
?
-
-
enzyme introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.18189 and 2.11.190
-
-
-
additional information
?
-
enzyme introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.1.1.189 and 2.1.1.190
-
-
-
additional information
?
-
-
enzyme introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.1.1.189 and 2.1.1.190
-
-
-
additional information
?
-
replacement of U747 in substrate 5'-740GGCACGUUGAAAAGUGCC757-3' by A, C, or G completely abolishes methylation
-
-
-
additional information
?
-
-
replacement of U747 in substrate 5'-740GGCACGUUGAAAAGUGCC757-3' by A, C, or G completely abolishes methylation
-
-
-
additional information
?
-
replacement of U747 in substrate 5'-740GGCACGUUGAAAAGUGCC757-3' by A, C, or G completely abolishes methylation
-
-
-
additional information
?
-
enzyme introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.18189 and 2.11.190
-
-
-
additional information
?
-
enzyme introduces C5 methylation at both U747 and U1939 of the 23S ribosomal RNA, i. e. catalyzes both the reactions of EC 2.1.1.189 and 2.1.1.190
-
-
-
additional information
?
-
-
the enzyme also methylates uracil1939 in 23S rRNA
-
-
?