2.1.1.186: 23S rRNA (cytidine2498-2'-O)-methyltransferase

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For detailed information about 23S rRNA (cytidine2498-2'-O)-methyltransferase, go to the full flat file.

Reaction

Synonyms

2O-ribose methyltransferase, Cm2498, RlmM, rRNA large subunit methyltransferase M, ygdE

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.186 23S rRNA (cytidine2498-2'-O)-methyltransferase

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Results	in table
4959	AA Sequence
3	Cloned(Commentary)
2	Cofactor
2	Crystallization (Commentary)
5	General Information
1	Metals/Ions
4	Natural Substrates/ Products (Substrates)
4	Organism
4	PDB ID
2	pH Optimum
3	Purification (Commentary)
1	Reaction
4	Reference
7	Substrates and Products (Substrate)
2	Subunits
10	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]

General Information

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General Information on EC 2.1.1.186 - 23S rRNA (cytidine2498-2'-O)-methyltransferase

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evolution

2 entries

malfunction

Escherichia coli

P0ADR6

C2498 methylation and the putative second methylation observed in the wild-type (YgdE+) strain are completely absent in the DygdE strain. Inactivation of the ygdE gene leads to loss of methylation at nucleotide C2498. The loss of ygdE function causes a slight reduction in bacterial fitness

700284

physiological function

2 entries