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2.1.1.172: 16S rRNA (guanine1207-N2)-methyltransferase

This is an abbreviated version!
For detailed information about 16S rRNA (guanine1207-N2)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
guanine1207 in 16S rRNA
=
S-adenosyl-L-homocysteine
+
N2-methylguanine1207 in 16S rRNA

Synonyms

16 S RNA m2G1207 methyltransferase, 16S rRNA:(guanine-N2) methyltransferase, 16S rRNA:m2G1207 MTase, 16S rRNA:m2G966 MTase, EC 2.1.1.51, EC 2.1.1.52, ribosomal RNA small subunit methyltransferase C, RNA:(guanine-N2) methyltransferase RsmC, RsmC, yjjT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.172 16S rRNA (guanine1207-N2)-methyltransferase

Inhibitors

Inhibitors on EC 2.1.1.172 - 16S rRNA (guanine1207-N2)-methyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
EDTA
2 mM, markedly reduces the level of methylation
KNHDWGV
-
7-mer peptide that binds to the second strand of 16S h34 RNA. Binding of the peptide alters RNA structure and inhibits the binding of the ribosomal RNA small subunit methyltransferase C. The addition of the peptide also increases the lag phase of bacterial growth
Mg2+
6 mM, markedly reduces the level of methylation