2.1.1.161: dimethylglycine N-methyltransferase

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For detailed information about dimethylglycine N-methyltransferase, go to the full flat file.

Reaction

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.161 dimethylglycine N-methyltransferase

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Results	in table
26	AA Sequence
2	Cloned(Commentary)
13	Inhibitors
4	KM Value [mM]
6	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
2	Organism
6	Pathway
2	pH Optimum
2	pH Range
3	Protein Variants
2	Purification (Commentary)
1	Reaction
2	Reference
5	Substrates and Products (Substrate)
2	Subunits
1	Systematic Name

Substrates Products

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Substrates Products on EC 2.1.1.161 - dimethylglycine N-methyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine

4 entries

additional information

?

-

Parasynechococcus marenigrum WH 8102

Q7U4Z9

several other amino acids tested as substrates and non of them serves as methyl group acceptor

671647

-

-

?

S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine

Aphanothece halophytica

-

-

659286

-

-

?

S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine

Aphanothece halophytica

-

synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine

659286

-

-

?

S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine

Parasynechococcus marenigrum WH 8102

Q7U4Z9

-

671647

-

-

?

S-adenosyl-L-methionine + N,N-dimethylglycine

S-adenosyl-L-homocysteine + N,N,N-trimethylglycine

Parasynechococcus marenigrum WH 8102

Q7U4Z9

synthesis of the compatible solute betaine de novo through the methylation of glycine, sarcosine and dimethylglycine with the methyl group from S-adenosylmethionine

671647

-

-

?