2.1.1.156: glycine/sarcosine N-methyltransferase

This is an abbreviated version!
For detailed information about glycine/sarcosine N-methyltransferase, go to the full flat file.

Reaction

Synonyms

glycine sarcosine dimethylglycine methyltransferase, glycine sarcosine methyltransferase, glycine sarcosine N-methyltransferase, GSDMT, Gsm, GsmA, GSMT, GSMT2, MXAN 7068

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.156 glycine/sarcosine N-methyltransferase

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Results	in table
2	Activating Compound
702	AA Sequence
3	Application
1	CAS Registry Number
11	Cloned(Commentary)
2	Cofactor
4	Expression
10	General Information
1	General Stability
2	IC50 Value
21	Inhibitors
24	KM Value [mM]
5	Metals/Ions
17	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
24	Organism
4	Pathway
5	PDB ID
9	pH Optimum
2	pH Range
1	pI Value
16	Protein Variants
7	Purification (Commentary)
2	Reaction
16	Reference
10	Specific Activity [micromol/min/mg]
51	Substrates and Products (Substrate)
9	Subunits
28	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

Reference

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Reference on EC 2.1.1.156 - glycine/sarcosine N-methyltransferase

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REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

657578

Nyyssola, A.; Reinikainen, T.; Leisola, M.

Characterization of glycine sarcosine N-methyltransferase and sarcosine dimethylglycine N-methyltransferase

Appl. Environ. Microbiol.

67

2044-2050

2001

Halorhodospira halochloris

11319079

brenda

659145

Nyyssola, A.; Kerovuo, J.; Kaukinen, P.; von Weymarn, N.; Reinikainen, T.

Extreme halophiles synthesize betaine from glycine by methylation

J. Biol. Chem.

275

22196-22201

2000

Halorhodospira halochloris, Halorhodospira halochloris (Q9KJ22), Actinopolyspora halophila (Q9KJ20)

10896953

brenda

659286

Waditee, R.; Tanaka, Y.; Aoki, K.; Hibino, T.; Jikuya, H.; Takano, J.; Takabe, T.

Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica

J. Biol. Chem.

278

4932-4942

2003

Aphanothece halophytica, Aphanothece halophytica (Q83WC4)

12466265

brenda

671647

Lu, W.D.; Chi, Z.M.; Su, C.D.

Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis

Arch. Microbiol.

186

495-506

2006

Parasynechococcus marenigrum WH 8102 (Q7U4Z8)

17019606

brenda

719715

Kimura, Y.; Kawasaki, S.; Yoshimoto, H.; Takegawa, K.

Glycine betaine biosynthesized from glycine provides an osmolyte for cell growth and spore germination during osmotic stress in Myxococcus xanthus

J. Bacteriol.

192

1467-1470

2010

Myxococcus xanthus

20023011

brenda

720836

Lai, S.J.; Lai, M.C.

Characterization and regulation of the osmolyte betaine synthesizing enzymes GSMT and SDMT from halophilic methanogen Methanohalophilus portucalensis

PLoS ONE

6

e25090

2011

Methanohalophilus portucalensis (F6KV61), Methanohalophilus portucalensis FDF1 (F6KV61)

21949863

brenda

733736

Niu, X.; Xiong, F.; Liu, J.; Sui, Y.; Zeng, Z.; Lu, B.; Liu, Y.

Co-expression of ApGSMT and ApDMT promotes biosynthesis of glycine betaine in rice (Oryza sativa L.) and enhances salt and cold tolerance

Environ. Exp. Bot.

104

16-25

2014

Aphanothece halophytica (Q83WC4)

-

brenda

734671

He, C.; He, Y.; Liu, Q.; Liu, T.; Liu, C.; Wang, L.; Zhang, J.

Co-expression of genes ApGSMT2 and ApDMT2 for glycinebetaine synthesis in maize enhances the drought tolerance of plants

Mol. Breed.

31

559-573

2013

Aphanothece halophytica

100029585

brenda

734932

Lai, S.J.; Lai, M.C.; Lee, R.J.; Chen, Y.H.; Yen, H.E.

Transgenic Arabidopsis expressing osmolyte glycine betaine synthesizing enzymes from halophilic methanogen promote tolerance to drought and salt stress

Plant Mol. Biol.

85

429-441

2014

Methanohalophilus portucalensis (F6KV61), Methanohalophilus portucalensis, Methanohalophilus portucalensis FDF-1 (F6KV61)

24803410

brenda

758143

Lai, S.J.; Deng, Y.C.; Lai, M.C.

Comparison of enzymatic traits between native and recombinant Glycine Sarcosine N-Methyltransferase from Methanohalophilus portucalensis FDF1T

PLoS ONE

11

e0168666

2016

Methanohalophilus portucalensis (F6KV61), Methanohalophilus portucalensis, Methanohalophilus portucalensis FDF-1 (F6KV61)

28036340

brenda

758369

Wu, W.L.; Lai, S.J.; Yang, J.T.; Chern, J.; Liang, S.Y.; Chou, C.C.; Kuo, C.H.; Lai, M.C.; Wu, S.H.

Phosphoproteomic analysis of Methanohalophilus portucalensis FDF1(T) identified the role of protein phosphorylation in methanogenesis and osmoregulation

Sci. Rep.

6

29013

2016

Methanohalophilus portucalensis (F6KV61), Methanohalophilus portucalensis, Methanohalophilus portucalensis FDF-1 (F6KV61)

27357474

brenda

Entries 1 - 20 of 11

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