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2.1.1.152: precorrin-6A synthase (deacetylating)

This is an abbreviated version!
For detailed information about precorrin-6A synthase (deacetylating), go to the full flat file.

Word Map on EC 2.1.1.152

Reaction

S-adenosyl-L-methionine
+
precorrin-5
+
H2O
=
S-adenosyl-L-homocysteine
+
precorrin-6A
+
acetate

Synonyms

CobF, precorrin-6X synthase (deacetylating)

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.152 precorrin-6A synthase (deacetylating)

Systematic Name

Systematic Name on EC 2.1.1.152 - precorrin-6A synthase (deacetylating)

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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)
The enzyme, which participates in the aerobic (late cobalt insertion) cobalamin biosythesis pathway, catalyses two reactions -the methylation of carbon C1 of precorrin-5, and its deacetylation, forming precorrin-6A. See EC 2.1.1.195, cobalt-precorrin-5B (C1)-methyltransferase, for the C1-methyltransferase that participates in the anaerobic cobalamin biosynthesis pathway.