2.1.1.148: thymidylate synthase (FAD)

This is an abbreviated version!
For detailed information about thymidylate synthase (FAD), go to the full flat file.

Reaction

Synonyms

A674R, complementing thymidylate synthase, FDTS, flavin dependent thymidylate synthase, flavin-dependent thymidylate synthase, flavin-dependent thymidylate synthase X, flavin-dependent TS, Thy1, thymidylate synthase 1, thymidylate synthase complementing protein, thymidylate synthase ThyX, thymidylate synthase X, ThyX, thyX-encoded thymidylate synthase, TSCP, TTHA1096

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.148 thymidylate synthase (FAD)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
14	Activating Compound
10362	AA Sequence
53	Application
1	CAS Registry Number
14	Cloned(Commentary)
123	Cofactor
16	Crystallization (Commentary)
1	Expression
2	General Information
8	IC50 Value
33	Inhibitors
10	Ki Value [mM]
17	KM Value [mM]
1	Metals/Ions
10	Molecular Weight [Da]
47	Natural Substrates/ Products (Substrates)
152	Organism
6	Pathway
137	PDB ID
1	pH Optimum
1	pH Range
1	Posttranslational Modification
44	Protein Variants
12	Purification (Commentary)
2	Reaction
5	Reaction Type
116	Reference
2	Storage Stability
123	Substrates and Products (Substrate)
20	Subunits
121	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
7	Temperature Stability [°C]
7	Turnover Number [1/s]

Organism

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Organism on EC 2.1.1.148 - thymidylate synthase (FAD)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Organism Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Aeropyrum pernix

-

657899

-

-

brenda

Aquifex aeolicus

-

657899

-

-

brenda

Bacillus anthracis

-

637235, 671555

-

-

brenda

Borreliella burgdorferi

-

637232, 637235

-

-

brenda

Campylobacter jejuni

-

637232, 637233, 637235, 658992

-

-

brenda

Chlamydia pneumoniae

-

637235

-

-

brenda

Chlamydia psittaci

-

637235

-

-

brenda

Chlamydia sp.

enzyme found in three different species

637232

-

-

brenda

Chlamydia trachomatis

-

637235, 671555

-

-

brenda

Clostridioides difficile

-

637235

-

-

brenda

Clostridium botulinum

-

637235, 671555

-

-

brenda

Clostridium perfringens

-

637235

-

-

brenda

Corynebacterium diphtheriae

-

637235

-

-

brenda

Dictyostelium discoideum

-

637232, 637234, 637235

-

-

brenda

Ehrlichia chaffeensis

-

637235

-

-

brenda

Halobacterium salinarum

-

637233

-

-

brenda

Helicobacter pylori

6 entries

Helicobacter pylori 26695

-

757894

O26061

UniProt

brenda

Helicobacter pylori SS1

-

720992

Q5UVJ4

UniProt

brenda

Mycobacterium avium

-

637235

-

-

brenda

Mycobacterium leprae

2 entries

Mycobacterium tuberculosis

9 entries

Mycobacterium tuberculosis ATCC 25618

-

756170

P9WG57

UniProt

brenda

Mycobacterium tuberculosis H37Rv

-

671555, 681384, 698579, 756483

P9WG57

UniProt

brenda

Mycobacterium tuberculosis variant bovis

-

637235

-

-

brenda

no activity in Archaeoglobus fulgidus

-

657899

-

-

brenda

no activity in Corynebacterium glutamicum strain NCHU 87078

-

718969

-

-

brenda

no activity in Homo sapiens

-

671555

-

-

brenda

no activity in Methanocaldococcus jannaschii

-

657899

-

-

brenda

no activity in Methanopyrus kandleri

AV19

657899

-

-

brenda

no activity in Methanopyrus kandleri AV19

AV19

657899

-

-

brenda

no activity in Methanothermobacter thermoautotrophicus

-

657899

-

-

brenda

Paramecium bursaria Chlorella virus 1

3 entries

Paramecium bursaria Chlorella virus-1

-

659429, 671555, 680675

-

-

brenda

Pyrobaculum aerophilum

-

657899

-

-

brenda

Pyrococcus abyssi

2 entries

Pyrococcus furiosus

3 entries

Pyrococcus horikoshii

-

637232, 657899

-

-

brenda

Rhodobacter capsulatus

-

692837

-

-

brenda

Rhodobacter capsulatus MT1131

-

692837

-

-

brenda

Rhodococcus sp.

-

637235

-

-

brenda

Rickettsia conorii

-

637235

-

-

brenda

Rickettsia prowazekii

-

637232, 637235

-

-

brenda

Rickettsia sp.

-

671555

-

-

brenda

Saccharolobus solfataricus

-

637232, 657899

-

-

brenda

Sulfurisphaera tokodaii

-

657899

-

-

brenda

Thermoplasma acidophilum

-

657899

-

-

brenda

Thermoplasma volcanium

-

657899

-

-

brenda

Thermotoga maritima

5 entries

Thermotoga maritima ATCC 43589

-

719663, 734029, 734346

Q9WYT0

SwissProt

brenda

Thermotoga maritima DSM 3109

2 entries

Thermus thermophilus

-

755734

Q5SJB8

UniProt

brenda

Thermus thermophilus DSM 579

-

755734

Q5SJB8

UniProt

brenda

Treponema denticola

-

637235

-

-

brenda

Treponema palladium

-

671555

-

-

brenda

Treponema pallidum

-

637232, 637235

-

-

brenda

Trichodesmium erythraeum

-

659052

-

-

brenda

Helicobacter pylori

-

637232

Q9ZJ93

UniProt

brenda

Helicobacter pylori

-

637235

-

-

brenda

Helicobacter pylori

-

637235

Q9ZJ93

UniProt

brenda

Helicobacter pylori

-

660374, 671555, 700990, 720985

-

-

brenda

Helicobacter pylori

-

720992

Q5UVJ4

UniProt

brenda

Helicobacter pylori

-

757894

O26061

UniProt

brenda

Mycobacterium leprae

-

637235, 671555

-

-

brenda

Mycobacterium leprae

simultaneous occurrence of thyA and thyX

637235

-

-

brenda

Mycobacterium tuberculosis

-

637232, 637235

-

-

brenda

Mycobacterium tuberculosis

-

671555

P9WG57

UniProt

brenda

Mycobacterium tuberculosis

-

681375

-

-

brenda

Mycobacterium tuberculosis

-

681384

P9WG57

UniProt

brenda

Mycobacterium tuberculosis

-

694812

-

-

brenda

Mycobacterium tuberculosis

-

698579

P9WG57

UniProt

brenda

Mycobacterium tuberculosis

-

733512

-

-

brenda

Mycobacterium tuberculosis

-

756170, 756483

P9WG57

UniProt

brenda

Mycobacterium tuberculosis

simultaneous occurrence of thyA and thyX

637235

-

-

brenda

Paramecium bursaria Chlorella virus 1

-

691285

O41156

UniProt

brenda

Paramecium bursaria Chlorella virus 1

-

700990

-

-

brenda

Paramecium bursaria Chlorella virus 1

-

733298, 756968

O41156

UniProt

brenda

Pyrococcus abyssi

-

637232

Q9UZ51

UniProt

brenda

Pyrococcus abyssi

-

657899

-

-

brenda

Pyrococcus furiosus

-

671555

-

-

brenda

Pyrococcus furiosus

DSM 3638

657899

-

-

brenda

Pyrococcus furiosus

DSM3638

678023

Q8U3C9

SwissProt

brenda

Thermotoga maritima

-

637234, 637235

Q9WYT0

SwissProt

brenda

Thermotoga maritima

-

657899, 671555, 679184, 691759

-

-

brenda

Thermotoga maritima

-

700395, 719663, 734029, 734346, 756968, 757387

Q9WYT0

SwissProt

brenda

Thermotoga maritima

enzyme additionally shows oxidase activity

697906

Q9WYT0

SwissProt

brenda

Thermotoga maritima

TM0449

637235, 658015

Q9WYT0

SwissProt

brenda

Thermotoga maritima DSM 3109

-

756968, 757387

Q9WYT0

SwissProt

brenda

Thermotoga maritima DSM 3109

TM0449

637235, 658015

Q9WYT0

SwissProt

brenda