2.1.1.145: trans-aconitate 3-methyltransferase
This is an abbreviated version!
For detailed information about trans-aconitate 3-methyltransferase, go to the full flat file.
Reaction
Synonyms
AGR110Wp, Tmt1 methyltransferase, trans-aconitate 3-methyltransferase, trans-aconitate methyltransferase
ECTree
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Substrates Products
Substrates Products on EC 2.1.1.145 - trans-aconitate 3-methyltransferase
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REACTION DIAGRAM
S-adenosyl-L-methionine + (2R,3R)/(2S,3S)-3-isopropylmalate
S-adenosyl-L-homocysteine + ?
-
poor substrate
-
-
?
S-adenosyl-L-methionine + (2R,3S)-3-isopropylmalate
S-adenosyl-L-homocysteine + ?
-
-
-
-
?
S-adenosyl-L-methionine + (2S,3R)-3-isopropylmalate
S-adenosyl-L-homocysteine + ?
-
-
-
-
?
S-adenosyl-L-methionine + 2-(1-methylethylidine)succinate
S-adenosyl-L-homocysteine + ?
-
-
-
-
?
S-adenosyl-L-methionine + 3-butylmalate
S-adenosyl-L-homocysteine + ?
-
-
-
-
?
S-adenosyl-L-methionine + cis-aconitate
S-adenosyl-L-homocysteine + (Z)-2-(methoxycarbonylmethyl)butenedioate
-
-
-
-
?
S-adenosyl-L-methionine + isopropylfumarate
S-adenosyl-L-homocysteine + ?
-
poor substrate
-
-
?
S-adenosyl-L-methionine + isopropylmaleate
S-adenosyl-L-homocysteine + ?
-
-
-
-
?
S-adenosyl-L-methionine + itaconate
S-adenosyl-L-homocysteine + ?
-
-
-
-
?
S-adenosyl-L-methionine + trans-aconitate
S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate
S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate
-
-
-
?
S-adenosyl-L-methionine + trans-aconitate
S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate
-
-
-
-
?
?
-
-
the enzyme may work in two different pathways in two different ways: for detoxification in the citric acid cycle and for a possibly novel biosynthetic branch reaction of the leucine biosynthetic pathway
-
-
?
additional information
?
-
-
no activity as substrate: 2-isopropylmalate
-
-
?