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2.1.1.128: (RS)-norcoclaurine 6-O-methyltransferase

This is an abbreviated version!
For detailed information about (RS)-norcoclaurine 6-O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.128

Reaction

S-adenosyl-L-methionine
+
(RS)-norcoclaurine
=
S-adenosyl-L-homocysteine
 +
(RS)-coclaurine

Synonyms

(R,S)-norcoclaurine 6-O-methyltransferase, (S)-Coclaurine N-methyltransferase, (S)-norcoclaurine 6-O-methyltransferase, (S)-norcoclaurine-6-O-methyltransferase, 3’-hydroxy-N-methylcoclaurine 4’-O-methyltransferase, 6-OMT, 6OMT, 6OMT1, 6OMT2, 7OMT, Ec4’OMT, Methyltransferase, (S)-coclaurine N-, Methyltransferase, norlaudanosoline, NLS-OMT, Norcoclaurine 6-O-methyltransferase, Ps6OMT, S-Adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase, S-Adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase, S-Adenosylmethionine:(R),(S)-norlaudanosoline-6-O-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.128 (RS)-norcoclaurine 6-O-methyltransferase

Substrates Products

Substrates Products on EC 2.1.1.128 - (RS)-norcoclaurine 6-O-methyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-homocysteine + (S)-reticuline
S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine
show the reaction diagram
-
-
-
?
S-Adenosyl-L-methionine + (R)-norlaudanosoline
S-Adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline
show the reaction diagram
S-Adenosyl-L-methionine + (R,S)-2,3-dihydroxy-9,10-dimethoxytetrahydroprotoberberine
S-Adenosyl-L-homocysteine + ?
show the reaction diagram
-
5% of the activity with (S)-norlaudanosoline
-
-
?
S-Adenosyl-L-methionine + (R,S)-4'-O-methylnorlaudanosoline
S-Adenosyl-L-homocysteine + norprotosinomenine
show the reaction diagram
-
34% of the activity with (S)-norlaudanosoline
-
?
S-Adenosyl-L-methionine + (R,S)-5'-O-methylnorlaudanosoline
S-Adenosyl-L-homocysteine + 6-O-methyllaudanosoline
show the reaction diagram
-
81% of the activity with (S)-norlaudanosoline
-
?
S-adenosyl-L-methionine + (R,S)-norlaudanosoline
S-adenosyl-L-homocysteine + (RS)-6-O-methylnorlaudanosoline
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + (R,S)-norlaudanosoline
S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline
show the reaction diagram
S-adenosyl-L-methionine + (RS)-norcoclaurine
S-adenosyl-L-homocysteine + (RS)-coclaurine
show the reaction diagram
S-adenosyl-L-methionine + (S)-norcoclaurine
S-adenosyl-L-homocysteine + (S)-coclaurine
show the reaction diagram
S-adenosyl-L-methionine + (S)-norlaudanosoline
S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline
show the reaction diagram
S-adenosyl-L-methionine + (S)-norlaudanosoline
S-adenosyl-L-homocysteine + 6-O-methylnorlaudanosoline + 7-O-methylnorlaudanosoline
show the reaction diagram
S-Adenosyl-L-methionine + (S)-scoulerine
S-Adenosyl-L-homocysteine + jatrorrhizine
show the reaction diagram
-
1% of the activity with (S)-norlaudanosoline
-
?
S-Adenosyl-L-methionine + 2,3-dihydroxy-9,10-dimethoxyprotoberberine
S-Adenosyl-L-homocysteine + tetrahydrojatrorrhizine
show the reaction diagram
-
7% of the activity with (S)-norlaudanosoline
-
?
S-adenosyl-L-methionine + laudanosoline
?
show the reaction diagram
S-Adenosyl-L-methionine + laudanosoline
S-Adenosyl-L-homocysteine + tetrahydrocolumbamine
show the reaction diagram
-
79% of the activity with (S)-norlaudanosoline
-
?
S-Adenosyl-L-methionine + norcoclaurine
S-Adenosyl-L-homocysteine + ?
show the reaction diagram
-
(S)-norcoclaurine and (R)-norcoclaurine
-
-
?