2.1.1.122: (S)-tetrahydroprotoberberine N-methyltransferase

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For detailed information about (S)-tetrahydroprotoberberine N-methyltransferase, go to the full flat file.

Reaction

Synonyms

(S)-tetrahydroprotoberberine cis-N-methyltransferase, (S)-Tetrahydroprotoberberine-cis-N-methyltransferase, Methyltransferase, tetrahydroberberine N-, S-Adenosyl-L-methionine: (S)-7,8,13,14-tetrahydroberberine-cis-N-methyltransferase, S-Adenosyl-L-methionine:tetrahydroberberine-cis-N-methyltransferase, S-adenosyl-L-methionine:tetrahydroprotoberberine cis-N-methyltransferase, S-Adenosylmethionine:tetrahydroberberine-N-methyltransferase, Tetrahydroberberine cis-N-methyltransferase, TNMT

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.122 (S)-tetrahydroprotoberberine N-methyltransferase

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Results	in table
2	Activating Compound
5	AA Sequence
1	Application
1	CAS Registry Number
2	Cloned(Commentary)
13	Inhibitors
12	KM Value [mM]
2	Localization
2	Metals/Ions
6	Molecular Weight [Da]
19	Organism
6	Pathway
5	pH Optimum
3	pH Range
5	Purification (Commentary)
1	Reaction
1	Reaction Type
18	Reference
10	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
31	Substrates and Products (Substrate)
1	Subunits
28	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]

pH Range

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pH Range on EC 2.1.1.122 - (S)-tetrahydroprotoberberine N-methyltransferase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5 - 9

Papaver somniferum

Q108P1

recombinant protein, half-maximal activity estimated at pH 6.8 and 8.2

674802

6.5 - 8

Sanguinaria canadensis

-

pH 6.5: about 55% of maximal activity, pH 8.0: about 65% of maximal activity

15205

6.6 - 9.1

Eschscholzia californica

-

about 50% of maximal activity at pH 6.6 and 9.1

15206