2.1.1.11: magnesium protoporphyrin IX methyltransferase

This is an abbreviated version!
For detailed information about magnesium protoporphyrin IX methyltransferase, go to the full flat file.

Reaction

Synonyms

(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase, BchM, ChlM, LOC_Os06g04150, magnesium protoporphyrin IX methyltransferase, magnesium protoporphyrin methyltransferase, magnesium protoporphyrin O-methyltransferase, methyltransferase, magnesium protoporphyrin, Mg-protoporphyrin IX methyltransferase, MgPIXMT protein, MgPMT, S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase, Ygl18

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.11 magnesium protoporphyrin IX methyltransferase

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Results	in table
4	Activating Compound
1026	AA Sequence
1	Application
1	CAS Registry Number
14	Cloned(Commentary)
3	Cofactor
1	Crystallization (Commentary)
2	Expression
5	General Information
1	General Stability
34	Inhibitors
4	Ki Value [mM]
14	KM Value [mM]
11	Localization
3	Metals/Ions
8	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
31	Organism
8	Pathway
3	PDB ID
6	pH Optimum
2	pH Range
2	Posttranslational Modification
12	Protein Variants
11	Purification (Commentary)
5	Reaction
4	Reaction Type
30	Reference
14	Source Tissue
3	Specific Activity [micromol/min/mg]
57	Substrates and Products (Substrate)
4	Subunits
25	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
5	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.1.1.11 - magnesium protoporphyrin IX methyltransferase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1,10-phenanthroline

Cereibacter sphaeroides

-

-

485101

8-hydroxyquinoline

Cereibacter sphaeroides

-

-

485101

AgNO3

Cereibacter sphaeroides

-

-

485101

chlorophyllide a

Triticum aestivum

-

-

485107

cobalt II-protoporphyrin

Rhodobacter capsulatus

P26236

non-substrate metalloporphyrin, competitive, assay described

684982

Diphenylthiocarbazone

Cereibacter sphaeroides

-

-

485101

ferric protoporphyrin

Cereibacter sphaeroides

-

-

485101

Ferrous protoporphyrin

Cereibacter sphaeroides

-

-

485101

hemin

Hordeum vulgare

-

noncompetitive with respect to magnesium protoporphyrin

485106

iodoacetic acid

Cereibacter sphaeroides

-

-

485101

magnesium protoporphyrin IX monomethyl ester

Triticum aestivum

-

-

485107

magnesium protoporphyrin monomethyl ester

2 entries

manganese III-protoporphyrin

Rhodobacter capsulatus

P26236

non-substrate metalloporphyrin, non-competitive or un-competitive, assay described

684982

Manganic protoporphyrin

Cereibacter sphaeroides

-

-

485101

Manganous protoporphyrin

Cereibacter sphaeroides

-

-

485101

MnCl2

Cereibacter sphaeroides

-

-

485101

PCMB

Cereibacter sphaeroides

-

-

485101

pheophorbide a

Triticum aestivum

-

stronger inhibitor than the corresponding Mg-chelate

485107

protochlorophyllide a

Triticum aestivum

-

-

485107

Protopheophorbide

Triticum aestivum

-

stronger inhibitor than the corresponding Mg-chelate

485107

S-adenosyl-L-homocysteine

6 entries

S-adenosylethionine

2 entries

sinefungin

Hordeum vulgare

-

selective inhibitor and potentially usefull tool for chlorophyll biosynthetic studies

485112

Sodium azide

Cereibacter sphaeroides

-

-

485101

Sodium diethyldithiocarbamate

Cereibacter sphaeroides

-

-

485101

ZnSO4

Cereibacter sphaeroides

-

-

485101

additional information

Rhodobacter capsulatus

P26236

higher magnesium ion concentrations above 3.8 mM inhibit enzyme activity in presence or absence of magnesium-chelatase subunits or BSA

684982

-

magnesium protoporphyrin monomethyl ester

Euglena gracilis

-

noncompetitive inhibitor of S-adenosyl-L-methionine

485104

magnesium protoporphyrin monomethyl ester

Rhodobacter capsulatus

P26236

non-competitive product inhibition

684982

S-adenosyl-L-homocysteine

Cereibacter sphaeroides

-

-

485101

S-adenosyl-L-homocysteine

Cereibacter sphaeroides

-

non-competitive inhibitor of Mg protoporphyrin

485103

S-adenosyl-L-homocysteine

Euglena gracilis

-

competitive with S-adenosyl-L-methionine

485104

S-adenosyl-L-homocysteine

Hordeum vulgare

-

competitive with S-adenosyl-L-methionine

485106

S-adenosyl-L-homocysteine

Rhodobacter capsulatus

P26236

non-competitive product inhibition

684982

S-adenosyl-L-homocysteine

Synechocystis sp. PCC 6803

-

competitive with respect to S-adenosyl-L-methionine and mixed inhibition with respect to magnesium protoporphyrin

485113

S-adenosylethionine

Euglena gracilis

-

competitive with S-adenosyl-L-methionine

485104

S-adenosylethionine

Hordeum vulgare

-

competitive with S-adenosyl-L-methionine

485106