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0.2
1,2,3,4-tetrahydroisoquinoline
-
-
0.548
2-methoxypyridine
pH 8.6, 37°C
2.029
2-methylpyridine
pH 8.6, 37°C
0.727
3-acetylpyridine
pH 8.6, 37°C
0.335
4-methylnicotinamide
pH 8.6, 37°C
0.125
4-phenylpyridine
pH not specified in the publication, temperature not specified in the publication
0.003 - 11.8
nicotinamide
1.326
nicotinimidamide
pH 8.6, 37°C
0.09
norharman
pH 8.6, 37°C
0.364
quinoline 3-carboxamide
pH 8.6, 37°C
0.00176 - 3.5
S-adenosyl-L-methionine
0.613
tetrahydroisoquinoline
pH 8.6, 37°C
0.111
Thionicotinamide
pH 8.6, 37°C
additional information
additional information
-
0.087
Isoquinoline
pH 8.6, 37°C
0.003
nicotinamide
pH 8.6, 37°C
0.02
nicotinamide
pH 7.5, temperature not specified in the publication
0.105
nicotinamide
K100A/E101A/E103A mutant protein, pH 8.6, 37°C
0.199
nicotinamide
pH 8.6, 37°C
0.24
nicotinamide
Y20F mutant protein, pH 8.6, 37°C
0.38
nicotinamide
-
recombinant protein
0.4
nicotinamide
0.43-0.38 mM, wild type protein, pH 8.6, 37°C
0.63
nicotinamide
Y20A mutant protein, pH 8.6, 37°C
1.02
nicotinamide
-
pH 7.2, 37°C, liver homogenate
1.36
nicotinamide
-
pH 7.2, 37°C, liver homogenate
11.8
nicotinamide
D197A mutant protein, pH 8.6, 37°C
0.01
Quinoline
pH 8.6, 37°C
0.609
Quinoline
pH 8.6, 37°C
0.00176
S-adenosyl-L-methionine
-
-
0.0018
S-adenosyl-L-methionine
-
-
0.002
S-adenosyl-L-methionine
0.0018-0.0022 mM, wild type protein, pH 8.6, 37°C
0.0022
S-adenosyl-L-methionine
-
recombinant protein
0.005
S-adenosyl-L-methionine
K100A/E101A/E103A mutant protein, pH 8.6, 37°C
0.0065
S-adenosyl-L-methionine
-
-
0.0085
S-adenosyl-L-methionine
pH 8.6, 37°C
0.01
S-adenosyl-L-methionine
pH 8.6, 37°C
0.016
S-adenosyl-L-methionine
-
-
0.024
S-adenosyl-L-methionine
pH 7.5, temperature not specified in the publication
0.028
S-adenosyl-L-methionine
Y20F mutant protein, pH 8.6, 37°C
2.73
S-adenosyl-L-methionine
D197A mutant protein, pH 8.6, 37°C
3.5
S-adenosyl-L-methionine
Y20A mutant protein, pH 8.6, 37°C
additional information
additional information
-
Michaelis-Menten kinetics
-
additional information
additional information
-
Michaelis-Menten kinetics
-
additional information
additional information
-
Michaelis-Menten kinetics, the Km value cannot be determined using Michaelis-Menten kinetic modelling
-
2.1.1.1 nicotinamide N-methyltransferase
results (
results (
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