2.1.1.1: nicotinamide N-methyltransferase
This is an abbreviated version!
For detailed information about nicotinamide N-methyltransferase, go to the full flat file.
Reaction
+
+
=
+
Synonyms
ANMT-1, B0303.2, methyltransferase, nicotinamide, nicotinamide N-methyl transferase, nicotinamide N-methyltransferase, NNMT
ECTree
KCat KM Value
KCat KM Value on EC 2.1.1.1 - nicotinamide N-methyltransferase
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0.005
2-methoxypyridine
pH 8.6, 37°C
0.005
2-methylpyridine
pH 8.6, 37°C
0.02
3-acetylpyridine
pH 8.6, 37°C
0 - 273
4-methylnicotinamide
pH 8.6, 37°C
0.0008
4-phenylpyridine
pH not specified in the publication, temperature not specified in the publication
0.197
Isoquinoline
pH 8.6, 37°C
0.01
nicotinimidamide
pH 8.6, 37°C
0.003
norharman
pH 8.6, 37°C
0.02
quinoline 3-carboxamide
pH 8.6, 37°C
0.009 - 39
S-adenosyl-L-methionine
0.074
tetrahydroisoquinoline
pH 8.6, 37°C
0.3
Thionicotinamide
pH 8.6, 37°C
0.003
nicotinamide
D197A mutant protein, pH 8.6, 37°C
0.005
nicotinamide
Y20A mutant protein, pH 8.6, 37°C
0.17
nicotinamide
Y20F mutant protein, pH 8.6, 37°C
0.19
nicotinamide
0.18-0.2 1/sec*mM, wild type protein, pH 8.6, 37°C
0.51
nicotinamide
pH 8.6, 37°C
0.8
nicotinamide
K100A/E101A/E103A mutant protein, pH 8.6, 37°C
4.7
nicotinamide
pH 8.6, 37°C
0.076
Quinoline
pH 8.6, 37°C
1.1
Quinoline
pH 8.6, 37°C
0.009
S-adenosyl-L-methionine
Y20A mutant protein, pH 8.6, 37°C
0.013
S-adenosyl-L-methionine
D197A mutant protein, pH 8.6, 37°C
0.75
S-adenosyl-L-methionine
pH 8.6, 37°C
1.5
S-adenosyl-L-methionine
Y20F mutant protein, pH 8.6, 37°C
17
S-adenosyl-L-methionine
K100A/E101A/E103A mutant protein, pH 8.6, 37°C
39
S-adenosyl-L-methionine
35-43 1/sec*mM, wild type protein, pH 8.6, 37°C