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1.8.98.1: dihydromethanophenazine:CoB-CoM heterodisulfide reductase

This is an abbreviated version!
For detailed information about dihydromethanophenazine:CoB-CoM heterodisulfide reductase, go to the full flat file.

Word Map on EC 1.8.98.1

Reaction

CoB
+
CoM
+
methanophenazine
=
CoM-S-S-CoB
+
dihydromethanophenazine

Synonyms

Co:CoM-S-S-CoB oxidoreductase system, CO:heterodisulfide oxidoreductase system, CoB-S-S-CoM reductase, Coenzyme B-Coenzyme M heterodisulfide reductase, coenzyme F420:heterodisulfide oxidoreductase, CoM-S-S-HTP reductase, DsrE2A, DsrK, F420H2-dependent CoM-S-S-HTP reductase, F420H2-dependent heterodisulfide reductase, Fdx:CoMS-SCoB oxidoreductase, ferredoxin- and F420H2-dependent, electron-bifurcating, heterodisulfide reductase, H2:heterodisulfide oxidoreductase, HDR, HdrA, hdrA2B2C2, HdrABC, HdrB, HdrB1, HdrB2, HdrC, HdrC1, HdrC2, HdrD, heterodisulfide reductase, More, SdhC, soluble heterodisulfide reductase, Vlud

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.98 With other, known, physiological acceptors
                1.8.98.1 dihydromethanophenazine:CoB-CoM heterodisulfide reductase

Natural Substrates Products

Natural Substrates Products on EC 1.8.98.1 - dihydromethanophenazine:CoB-CoM heterodisulfide reductase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
coenzyme B + coenzyme M + methanophenazine
N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + dihydromethanophenazine
show the reaction diagram
coenzyme B + coenzyme M + methanophenazine
N-(7-[(2-sulfoethyl)dithio]heptanoyl)-O3-phospho-L-threonine + dihydromethanophenazine
show the reaction diagram
coenzyme B + coenzyme M + methanophenazine
N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
show the reaction diagram
coenzyme B-coenzyme M disulfide + dihydromethanophenazine
coenzyme B + coenzyme M + methanophenazine
show the reaction diagram
coenzyme B-coenzyme M disulfide + reduced ferredoxin
coenzyme B + coenzyme M + ferredoxin
show the reaction diagram
DsrC protein disulfide + dihydromethanophenazine
DsrC protein + methanophenazine
show the reaction diagram
N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + coenzyme F420H2
coenzyme B + coenzyme M + coenzyme F420
show the reaction diagram
N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + dihydromethanophenazine
coenzyme B + coenzyme M + methanophenazine
show the reaction diagram
-
-
-
-
?
N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + H2
coenzyme B + coenzyme M
show the reaction diagram
N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced cytochrome b
coenzyme B + coenzyme M + oxidized cytochrome b
show the reaction diagram
-
electron transfer by a CO dehydrogenase in complex with the heterodisulfide oxidoreductase, no H2 uptake in vivo, reaction is part of the overall reduction of acetate to methane and H2O, also providing a proton-translocation redox system to drive ATP formation
-
-
?
additional information
?
-