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1.8.1.2: assimilatory sulfite reductase (NADPH)

This is an abbreviated version!
For detailed information about assimilatory sulfite reductase (NADPH), go to the full flat file.

Word Map on EC 1.8.1.2

Reaction

hydrogen sulfide
+ 3 NADP+ + 3 H2O =
sulfite
+ 3 NADPH + 3 H+

Synonyms

CNG03990, coenzyme F420-dependent sulfite reductase, CysI, CysIJ, desulforubidin, EC 1.8.99.1, Fsr, H2S-NADP oxidoreductase, MET10, NADPH-dependent assimilatory sulfite reductase, NADPH-dependent sulfite reductase, NADPH-sulfite reductase, reductase, sulfite (reduced nicotinamide adenine dinucleotide phosphate), SIR, SIR-FP, SIR-HP, SiR/SiRHP, SIRHP, sulfite reductase, sulfite reductase hemo-subunit

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.2 assimilatory sulfite reductase (NADPH)

Inhibitors

Inhibitors on EC 1.8.1.2 - assimilatory sulfite reductase (NADPH)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2'-AMP
-
NADPH-sulfite reductase and NADPH-cytochrome c reductase
8-hydroxyquinoline
-
-
arsenite
Ca2+
-
strong inhibition
Co2+
-
strong inhibition
Cu2+
-
strong inhibition
Fe2+
-
strong inhibition
Fe3+
-
strong inhibition
Hg2+
-
strong inhibition
iodoacetic acid
-
-
iodonium diphenyl chloride
-
acts on NADPH- and FAD-binding domain of flavoprotein component
KCN
-
complete inhibition at 1 mM
Low ionic strength
-
NADPH-dependent activities
-
NADP+
o-phenanthroline
-
-
p-chloromercuribenzoate
-
NADPH-dependent activities
p-Mercuriphenylsulfonate
PCMB
-
complete inhibition at 1 mM
sulfate
-
-
Sulfide
additional information
-
inhibitory potency of metal ions, overview, no inhibition by Na+, K+, and Mg2+
-