1.7.3.3: factor-independent urate hydroxylase
This is an abbreviated version!
For detailed information about factor-independent urate hydroxylase, go to the full flat file.
Word Map on EC 1.7.3.3
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1.7.3.3
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hyperuricemia
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peroxisomal
-
xanthine
-
allopurinol
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gout
-
purine
-
catalase
-
allantoin
-
biosensors
-
electrode
-
hematologic
-
creatinine
-
oxonic
-
febuxostat
-
allantoinase
-
hyperkalemia
-
hypoxanthine
-
prophylaxis
-
flavus
-
hyperphosphatemia
-
urate-lowering
-
ureide
-
methemoglobinemia
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pegylated
-
amperometric
-
uricosuric
-
hypocalcemia
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tophi
-
benzbromarone
-
hominoid
-
phosphotungstate
-
microbodies
-
hypouricemic
-
probenecid
-
utilis
-
pimecrolimus
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pharmacology
-
medicine
-
analysis
-
synthesis
-
weight-based
-
nodule-specific
-
miocene
-
drug development
- 1.7.3.3
- hyperuricemia
- peroxisomal
- xanthine
- allopurinol
- gout
- purine
- catalase
- allantoin
-
biosensors
-
electrode
-
hematologic
- creatinine
-
oxonic
- febuxostat
- allantoinase
- hyperkalemia
- hypoxanthine
-
prophylaxis
- flavus
- hyperphosphatemia
-
urate-lowering
-
ureide
- methemoglobinemia
-
pegylated
-
amperometric
-
uricosuric
-
hypocalcemia
-
tophi
- benzbromarone
-
hominoid
-
phosphotungstate
- microbodies
-
hypouricemic
- probenecid
- utilis
- pimecrolimus
- pharmacology
- medicine
- analysis
- synthesis
-
weight-based
-
nodule-specific
-
miocene
- drug development
Reaction
Synonyms
AaUO, AgUOX, dHU-wPU, ELITEK, Fasturtec, MVSM, N-35, Nodule specific uricase, Nodulin 35, Nodulin 35 homolog, Non-symbiotic uricase, oxidase, urate, Pucl, Rasburicase, Uaz, Uox, Urate oxidase, urate oxidoreductase, UriA, uric acid oxidase, uricase, uricase II, Uricoenzyme, Uricozyme
ECTree
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pH Optimum
pH Optimum on EC 1.7.3.3 - factor-independent urate hydroxylase
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6.5
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yield of recombinant uricase is significantly improved by the combined use of a high cell-density cultivation technique and a pH control strategy of switching culture pH from 5.5 to 6.5 in the induction phase
8.5
8.9
9.2
9.5
9.2
the unmodified uricase has a pH optimum of slightly below pH 9.2 which is not altered by modification with NHS esters of monomethoxy-poly(ethylene glycol)-5000 or monomethoxy-poly(ethylene glycol)-350