1.7.2.8: hydrazine dehydrogenase
This is an abbreviated version!
For detailed information about hydrazine dehydrogenase, go to the full flat file.
Word Map on EC 1.7.2.8
-
1.7.2.8
-
anammox
-
nitrite
-
rrna
-
candidatus
-
ammonium-oxidizing
-
kuenenia
-
scalindua
-
wastewater
-
reactor
-
brocadia
-
stuttgartiensis
-
sludge
-
anammoxosome
-
planctomycete
-
nitrosomonas
-
oxygen-limited
-
biogeochemical
-
influent
-
ladderane
-
wetland
-
denitrification
-
jettenia
-
dinitrogen
-
denitrifiers
-
environmental protection
- 1.7.2.8
-
anammox
- nitrite
- rrna
-
candidatus
-
ammonium-oxidizing
- kuenenia
- scalindua
-
wastewater
-
reactor
- brocadia
- stuttgartiensis
- sludge
- anammoxosome
-
planctomycete
- nitrosomonas
-
oxygen-limited
-
biogeochemical
-
influent
-
ladderane
-
wetland
-
denitrification
- jettenia
-
dinitrogen
-
denitrifiers
- environmental protection
Reaction
Synonyms
EC 1.7.99.8, HAO, HAOr-DH, HDH, hydrazine oxidoreductase, hydrazine-oxidizing enzyme, hydroxylamine oxidoreductase, hzoB
ECTree
1.7.2.8 hydrazine dehydrogenaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 1.7.2.8 - hydrazine dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
hydrazine + 2,6-dichloroindophenol
? + reduced 2,6-dichloroindophenol
-
-
-
?
hydrazine + 2,6-dichlorophenolindophenol
N2 + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
hydrazine + 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
? + reduced methylthiazolyltetrazolium bromide
reduction of 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide via phenazine methosulfate
-
-
?
hydrazine + 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
N2 + reduced 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
-
-
-
-
?
hydrazine + 4 bovine heart ferricytochrome c
N2 + 4 bovine heart ferrocytochrome c
-
-
-
-
?
hydrazine + ferricyanide
N2 + ferrocyanide
-
ferricyanide as the electron acceptor results in the highest specific activity. Hydrazine is solely converted to N2
-
-
?
hydrazine + ferricytochrome
N2 + ferrocytochrome
-
horse heart cytochrome. Hydrazine is solely converted to N2
-
-
?
hydrazine + methylthiazolyltetrazolium bromide
? + reduced methylthiazolyltetrazolium bromide
reduction of methylthiazolyltetrazolium bromide via phenazine methosulfate
-
-
?
hydrazine + methylthiazolyltetrazolium bromide
N2 + reduced methylthiazolyltetrazolium bromide
-
reduction of methylthiazolyltetrazolium bromide via phenazine methosulfate. Hydrazine is solely converted to N2
-
-
?
hydrazine + NH3 + 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
?
-
-
-
?
hydrazine + phenazine methosulfate
? + reduced phenazine methosulfate
-
-
-
?
hydroxylamine + 2 acceptor + H2O
nitrite + 2 reduced acceptor + H+
-
-
-
-
?
hydroxylamine + 2,6-dichlorophenolindophenol
N2O + reduced 2,6-dichlorophenolindophenol
-
horse heart cytochrome. The conversion of hydroxylamine by the enzyme results in the formation of NO and N2O. A small amount of NO2- is measured, but this is probably due to the chemical reaction of NO. No other nitrogen compounds are detected
small amounts of NO are also formed
-
?
hydroxylamine + 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
? + reduced 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
reduction of methylthiazolyltetrazolium bromide via phenazine methosulfate
-
-
?
hydroxylamine + ferricyanide
N2O + ferrocyanide
-
ferricyanide as the electron acceptor results in the highest specific activity. The conversion of hydroxylamine by the enzyme results in the formation of NO and N2O. A small amount of NO2- is measured, but this is probably due to the chemical reaction of NO. No other nitrogen compounds are detected
small amounts of NO are also formed
-
?
hydroxylamine + ferricytochrome
N2O + ferrocytochrome
-
horse heart cytochrome. The conversion of hydroxylamine by the enzyme results in the formation of NO and N2O. A small amount of NO2- is measured, but this is probably due to the chemical reaction of NO. No other nitrogen compounds are detected
small amounts of NO are also formed
-
?
hydroxylamine + methylthiazolyltetrazolium bromide
N2O + reduced methylthiazolyltetrazolium bromide
-
the conversion of hydroxylamine by the enzyme results in the formation of NO and N2O. A small amount of NO2- is measured, but this is probably due to the chemical reaction of NO. No other nitrogen compounds are detected
small amounts of NO are also formed
-
?
hydroxylamine + NH3 + 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
?
-
-
-
?
hydroxylamine + NH3 + phenazine methosulfate
NO2 + H2O + reduced phenazine methosulfate
-
-
-
?
hydrazine + 4 ferricytochrome c
N2 + 4 ferrocytochrome c
-
-
-
-
?
hydrazine + 4 ferricytochrome c
N2 + 4 ferrocytochrome c
-
-
-
-
?
hydrazine + ferricytochrome c
N2 + ferrocytochrome c
-
-
-
-
?
hydrazine + ferricytochrome c
N2 + ferrocytochrome c
-
highly specific for hydrazine oxidation activity
-
-
?
hydroxylamine + NH3 + cytochrome c-554
NO2 + H2O + reduced cytochrome c-554
-
-
-
-
?
hydroxylamine + NH3 + cytochrome c-554
NO2 + H2O + reduced cytochrome c-554
-
the ammonia-oxidizing bacterium Nitrosomonas europaea normally catalyzes the four-electron oxidation of hydroxylamine to nitrite, which is the second step in ammonia-dependent respiration. In the presence of methyl viologen monocation radical, HAO can catalyze the reduction of nitric oxide to ammonia, reaction of by cytochrome c nitrite reductase , EC 1.7.2.2, overview
-
-
?
additional information
?
-
-
the enzyme is involved in anaerobic ammonium oxidation. Anaerobic ammonium oxidation is very important in the oceanic nitrogen cycle
-
-
?
additional information
?
-
-
the enzyme is involved in the anaerobic oxidation of ammonium
-
-
?
additional information
?
-
-
the enzyme is involved in the pathway of anaerobic ammonium oxidation
-
-
?
additional information
?
-
-
methanol is not a substrate, no activity with NAD+, benzyl viologen and Wurster's blue. The enzyme from anaerobic ammonium-oxidizing (Anammox) enrichment culture is also capable of reducing NO to N2O with a specific activity of 2.9 units/mg at room temperature. Reduction of nitrite in the presence of reduced methyl viologen results in the production of N2O and some NO (below 5%). No other nitrogen compounds are detected. In the presence of ascorbate and PMS, no nitrite conversion is observed
-
-
?
additional information
?
-
-
HAO is an indispensable enzyme and well conserved in anammox bacteria
-
-
?
additional information
?
-
HAO is an indispensable enzyme and well conserved in anammox bacteria
-
-
?
additional information
?
-
hydrazine-oxidizing enzyme (HZO, wich has no activity with hydroxylamine) and hydroxylamine oxidoreductase (HAO, which oxidizes hydroxylamine and hydrazine) occur both in planctomycete KSU-1
-
-
?
additional information
?
-
-
hydrazine-oxidizing enzyme (HZO, wich has no activity with hydroxylamine) and hydroxylamine oxidoreductase (HAO, which oxidizes hydroxylamine and hydrazine) occur both in planctomycete KSU-1
-
-
?
additional information
?
-
no activity with NAD+, hydroxylamine is not a substrate for hydrazine-oxidizing enzyme HZOB
-
-
?
additional information
?
-
-
no activity with NAD+, hydroxylamine is not a substrate for hydrazine-oxidizing enzyme HZOB
-
-
?
additional information
?
-
-
the enzyme is involved in anaerobic ammonium oxidation. Anaerobic ammonium oxidation is very important in the oceanic nitrogen cycle
-
-
?
additional information
?
-
-
the enzyme is involved in the anaerobic oxidation of ammonium
-
-
?
additional information
?
-
-
hydroxylamine does not serve as a substrate
-
-
?
additional information
?
-
-
enzyme shows hydroxylamine oxidase, hydrazine oxidase, and nitrite reductase activities
-
-
?
additional information
?
-
-
the enzyme is involved in anaerobic ammonium oxidation. Anaerobic ammonium oxidation is very important in the oceanic nitrogen cycle
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of hydroxylamine to nitrite, with a complicate arrangement of heme groups in three subunits
-
-
?
additional information
?
-
-
the enzyme catalyzes the four-electron oxidation of NH2OH to nitrite under aerobic conditions, HAO reacts with NO radical and NH2OH under reducing conditions
-
-
?
