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1.7.2.6: hydroxylamine dehydrogenase

This is an abbreviated version!
For detailed information about hydroxylamine dehydrogenase, go to the full flat file.

Word Map on EC 1.7.2.6

Reaction

hydroxylamine
+
H2O
 + 4 ferricytochrome c =
nitrite
 + 4 ferrocytochrome c + 5 H+

Synonyms

EC 1.7.3.4, HAO, haoA, HCR, HOA, hydroxylamine cytochrome c554 oxidoreductase, hydroxylamine oxidase, hydroxylamine oxidoreductase, hydroxylamine-cytochrome c reductase, hydroxylamine:oxygen oxidoreductase, mHAO, NeHAO, NirK, NoHAO

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.2 With a cytochrome as acceptor
                1.7.2.6 hydroxylamine dehydrogenase

Inhibitors

Inhibitors on EC 1.7.2.6 - hydroxylamine dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2',2'-dipyridyl
-
50% inhibition at 0.1 mM
8-hydroxyquinoline
-
50% inhibition at 0.2 mM
azide
-
50% inhibition at 3.2 mM
Ba2+
-
46.47% residual activity at 5 mM
Ca2+
-
20.39% residual activity at 5 mM
Cd2+
-
decreases in hydroxylamine oxidoreductase-specific oxygen uptake rate followed by a recovery of hydroxylamine oxidoreductase-specific oxygen uptake rate above steady-state levels do occur upon exposure to Cd2+ concentrations of 0.03 mM and greater
Ce(NH4)2(NO3)6
-
0.1 mM, stimulates the rate of oxidation of NH2OH 2.6-fold and inhibits production of HNO2 by 40%
Co(NO3)2
-
0.1 mM, 70% inhibition of the rate of nitrite synthesis
Cu2+
-
81.76% residual activity at 5 mM
cyanide
-
active site inhibitor
diethyldithiocarbamate
-
inhibition of nitrate production at 0.1 mM
hydrazine
-
50% inhibition at 0.1 mM
hydroxyethyl-hydrazine
-
-
hydroxylamine
-
potent inhibitor
methyl-hydrazine
-
-
Na2S
-
50% inhibition at 0.3 mM
o-phenanthroline
-
50% inhibition at 0.12 mM
phenazine methosulfate
-
inhibitory above 0.1 mM
phenyl hydrazine
-
N2H3 protects
phenylhydrazine
Zn2+
-
85.34% residual activity at 5 mM
additional information
-