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1.7.2.2: nitrite reductase (cytochrome; ammonia-forming)

This is an abbreviated version!
For detailed information about nitrite reductase (cytochrome; ammonia-forming), go to the full flat file.

Word Map on EC 1.7.2.2

Reaction

NH3
+ 2 H2O + 6 ferricytochrome c =
nitrite
+ 6 ferrocytochrome c + 7 H+

Synonyms

ammonia-forming cytochrome c nitrite reductase, ccNiR, CcuHao, CfHao, CmHao, cNiR, cytochrome c NiR, cytochrome c nitrite reductase, cytochrome c nitrite reductase complex, cytochrome c-552, epsilonHao, epsilonproteobacterial hydroxylamine oxidoreductase, Glov_1042, haoA, hexaheme c-type cytochrome, More, multihaem c NiR, multiheme cytochrome c nitrite reductase, multiheme nitrite reductase, NiR, NiR cytochrome c552, nirB, NirC, nitrite reductase, NpHao, NrfA, NrfA2NrfH complex, NrfHA, octahaem cytochrome c nitrite reductase, SCO2486, SCO2488, TvNiR, WS0969

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.2 With a cytochrome as acceptor
                1.7.2.2 nitrite reductase (cytochrome; ammonia-forming)

Inhibitors

Inhibitors on EC 1.7.2.2 - nitrite reductase (cytochrome; ammonia-forming)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
azide
CN-
-
cyanide is a potent inhibitor of NrfA nitrite and hydroxylamine reductase activities
CuCl2
-
0.01 mM,70% inhibition; 0.1 mM, 69% inhibition
CuSO4
-
0.01 mM, 68% inhibition
Cyanate
-
-
cyanide
KCN
-
0.1 mM, 84% inhibition; 1 mM, 100%
KNO3
-
1 mM, 6% inhibition
NaN3
-
1 mM, 16% inhibition
nitrate
nitrite
substrate inhibition
NO
-
wild-type cultures are more sensitive to the addition of a pulse of NO when grown under fermentative conditions compared with anaerobic respiratory conditions, sensitivity of different wild-type and mutant strains, overview
phosphate
-
weak inhibitor
sulfate
thiocyanate
-
effective inhibitor
Zn2+
EDTA protects NrfA from zinc inhibition, zinc inhibition kinetics in presence or absence of EDTA, overview
additional information
-