1.6.99.1: NADPH dehydrogenase
This is an abbreviated version!
For detailed information about NADPH dehydrogenase, go to the full flat file.
Word Map on EC 1.6.99.1
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1.6.99.1
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endothelial
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l-name
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artery
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l-arginine
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nerve
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ng-nitro-l-arginine
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vasodilation
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vessel
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nnos
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lipopolysaccharide
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hypertension
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cardiovascular
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acetylcholine
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agonist
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cerebral
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nitrite
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cyclase
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nitroprusside
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endothelium-dependent
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coronary
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contractile
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aorta
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cgmp
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tone
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histochemistry
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ischemia
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cyclooxygenase
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dimethylarginine
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ng-monomethyl-l-arginine
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guanylate
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nomega-nitro-l-arginine
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indomethacin
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nmda
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ganglion
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innervation
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vasoactive
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guanylyl
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peroxynitrite
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vasoconstriction
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aminoguanidine
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phenylephrine
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vasorelaxation
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endothelium-derived
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myenteric
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cholinergic
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n-methyl-d-aspartate
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tetrahydrobiopterin
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erectile
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bh4
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precontracted
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analysis
-
synthesis
- 1.6.99.1
- endothelial
-
l-name
- artery
- l-arginine
- nerve
- ng-nitro-l-arginine
-
vasodilation
- vessel
- nnos
- lipopolysaccharide
- hypertension
- cardiovascular
- acetylcholine
- agonist
- cerebral
- nitrite
- cyclase
- nitroprusside
-
endothelium-dependent
- coronary
-
contractile
- aorta
- cgmp
-
tone
-
histochemistry
- ischemia
-
cyclooxygenase
- dimethylarginine
- ng-monomethyl-l-arginine
-
guanylate
- nomega-nitro-l-arginine
- indomethacin
- nmda
- ganglion
-
innervation
-
vasoactive
-
guanylyl
- peroxynitrite
-
vasoconstriction
- aminoguanidine
- phenylephrine
-
vasorelaxation
-
endothelium-derived
- myenteric
-
cholinergic
- n-methyl-d-aspartate
- tetrahydrobiopterin
-
erectile
- bh4
-
precontracted
- analysis
- synthesis
Reaction
Synonyms
2-cyclohexen-1-one, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate, diaphorase, dihydronicotinamide adenine dinucleotide phosphate dehydrogenase, EBP, Estrogen-binding protein, NADP-d, NADPH diaphorase, NADPH-d, NADPH-dehydrogenase, NADPH-dependent cyclohexenone reductase, NADPH-dependent diaphorase, NADPH-diaphorase, NADPH-methemoglobin reductase, NADPH2-dehydrogenase, NCR, nicotinamide adenine dinucleotide phosphate diaphorase, nitric oxide synthase, old yellow enzyme, Old yellow enzyme homolog, OYE, OYE1, OYE2, OYE3, reduced nicotinamide adenine dinucleotide phosphate dehydrogenase, SYE4, TPNH dehydrogenase, TPNH-diaphorase, triphosphopyridine diaphorase, triphosphopyridine nucleotide diaphorase, YqjM
ECTree
1.6.99.1 NADPH dehydrogenaseAdvanced search results
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results (Source Tissue
Source Tissue on EC 1.6.99.1 - NADPH dehydrogenase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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in a subpopulation of olfactory receptor neurones and in mechano-, thermo- and hygroreceptors on the antenna and in non-neuronal cells
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of piglet, crypt cells, glandular epithelium in the deeper submucosa has a very strong activity, villous epithelial cells show the most intense activity in the mucosa
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localized in discrete populations of neuronal somata and in olfactory glomeruli. NADPH-diaphorase activity is due to nitric oxide synthase, the glomerular NADPH-diaphorase activity is not due to nitric oxide synthase
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in neonatal animals, small, moderately stained NADPH-d-positive cells are identified in the vertical arm and in the elbowv of the rostral migratory stream. In adult and aging rats a few labeled cells could be also detected in the RMS horizontal arm. The number of NADPH-d-positive cells increases with advancing age
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cyclic changes dependent on the estrous cycle. Changes observed mostly in the luminal epithelium and some endometrial glands. Localization and correlation between NADPH-diaphorase and nitric oxide synthase isoforms
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fifteen albino Swiss mice between the 22nd and 55th post-natal days are exercised in the following modalities: voluntary (V), acrobatic (A), acrobatic/voluntary (AV) and forced (F) and compared to inactive group (I). The A group presented higher NADPH-d activity in the cerebellar granular layer than all other groups
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distribution of NADPH-diaphorase activity in different human cortical areas, remarkable laminar and interareal differences across areas
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sympathetic autonomic ganglia, no activity in paravertebral superior cervical ganglia or in perikarya of any sympathetic ganglion. The superior mesenteric ganglia of aged and diabetic rats, in which dysplasia is prominent, fail to show involvement of diaphorase containing nerve terminals
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hippocampal neuron, experimental epilepsy induced in rats by infusion of kainic acid into the lateral cerebral ventricles decreases the number of NADPH-diaphorase-positive neurons in the hippocampal formation by 55-79%
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hyperoxaluric rats show intense staining for NADPH-diaphorase when compared to control and L-Arg cosupplemented hyperoxaluric rats
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hyperoxaluric rats show intense staining for NADPH-diaphorase when compared to control and L-Arg cosupplemented hyperoxaluric rats
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medium and small, more common in neurons from ipsilateral ganglia
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the high-iron diet mice show significantly higher staining intensity of NADPH-diaphorase positive neurons in the paraventricular nucleus and lateral hypothalamic area than the normal- and low-iron diet mice
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hippocampal neuron, experimental epilepsy induced in rats by infusion of kainic acid into the lateral cerebral ventricles decreases the number of NADPH-diaphorase-positive neurons in the hippocampal formation by 55-79%
