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1.6.5.10: NADPH dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about NADPH dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.6.5.10

Reaction

NADPH
+
H+
 +
a quinone
=
NADP+
 +
a quinol

Synonyms

AKR1C9, ArsH, azoreductase, CBR4, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate (quinone), EC 1.6.99.6, MdaB, More, NADPH oxidase, NADPH quinone oxidoreductase, NADPH quinone oxidoreductase 1, NADPH quinone reductase, NADPH-dependent quinone reductase, NADPH-quinone oxidoreductase, NADPH:quinone oxidoreductase 1, NQO1, PA1225, PpAzoR, XAC2229, Zta1p

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.5 With a quinone or similar compound as acceptor
                1.6.5.10 NADPH dehydrogenase (quinone)

Specific Activity

Specific Activity on EC 1.6.5.10 - NADPH dehydrogenase (quinone)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.000003
substrate (R,S)-camphorquinone, mutant Y55F, pH 6.0, 25°C
0.00002
substrate (R,S)-camphorquinone, mutant Y55S, pH 6.0, 25°C
0.0005
-
medium alone
0.0006
0.0007
-
TNFalpha and LPS inhibit the beta-naphthoflavone induced increase in activity
0.0012
-
in presence of beta-naphthoflavone
0.0016
substrate 9,10-phenanthrenenquinone, mutant Y55S, pH 6.0, 25°C
0.0018
substrate 9,10-phenanthrenenquinone, mutant Y55F, pH 6.0, 25°C
0.0025
substrate (R,S)-camphorquinone, wild-type, pH 6.0, 25°C
0.0038
substrate acenaphthenequinone, wild-type, pH 6.0, 25°C
0.0044
substrate 9,10-phenanthrenenquinone, wild-type, pH 6.0, 25°C
1.097
-
activity of purified cytochrome b558 reconstituted with neutrophil membrane phospholipids, activation with arachidonic acid
1.258
-
activity of purified cytochrome b558 reconstituted with neutrophil membrane phospholipids, activation with sodiumdodecylsulfate
1067
-
pH 7.5, 30°C
additional information