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1.6.3.4: NADH oxidase (H2O-forming)

This is an abbreviated version!
For detailed information about NADH oxidase (H2O-forming), go to the full flat file.

Reaction

2 NADH + 2 H+ +

O2
= 2 NAD+ + 2 H2O

Synonyms

H2O-forming NADH oxidase, LrNox, NADH oxidase, nicotinamide adenine dinucleotide oxidase, NOX, Nox-2, NoxA, NoxE, SpNox, water-forming NADH oxidase, YODC

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.3 With oxygen as acceptor
                1.6.3.4 NADH oxidase (H2O-forming)

General Information

General Information on EC 1.6.3.4 - NADH oxidase (H2O-forming)

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
the inability of the nox2 mutant to grow aerobically is mainly due to an underlying defect in fatty acid biosynthesis. NAD+ depletion in the nox2 mutant results in reduced acetyl-CoA production, which perturbs fatty acid biosynthesis and hence blocks growth in aerobiosis
metabolism
physiological function