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1.5.98.2: 5,10-methylenetetrahydromethanopterin reductase

This is an abbreviated version!
For detailed information about 5,10-methylenetetrahydromethanopterin reductase, go to the full flat file.

Word Map on EC 1.5.98.2

Reaction

5-methyltetrahydromethanopterin
+
oxidized coenzyme F420
=
5,10-methylenetetrahydromethanopterin
+
reduced coenzyme F420

Synonyms

5,10-methylene-H4MPT reductase, coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase, EC 1.5.99.11, H(2)-dependent methylene-H(4)MPT dehydrogenase, H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase, H2-dependent methylenetetrahydromethanopterin dehydrogenase, Hmd, Mer, MK0524, MTBMA_c03270, N5,N10-methylenetetrahydromethanopterin reductase, N5,N10-methylenetetrahydromethanopterin reductase (coenzyme F420-dependent), N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.98 With other, known, physiological acceptors
                1.5.98.2 5,10-methylenetetrahydromethanopterin reductase

Substrates Products

Substrates Products on EC 1.5.98.2 - 5,10-methylenetetrahydromethanopterin reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5,10-methylenetetrahydromethanopterin + reduced coenzyme F420
5-methyltetrahydromethanopterin + oxidized coenzyme F420
show the reaction diagram
N5,N10-methylenetetrahydromethanopterin + reduced coenzyme F420
5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme F420
show the reaction diagram
N5,N10-methylenetetrahydromethanopterin + reduced coenzyme F420
5-methyl-5,6,7,8-tetrahydromethanopterin + oxidized coenzyme F420
show the reaction diagram
additional information
?
-
-
recombinantly overexpressed Mer is able to use NADPH and methylglyoxal to produce lactaldehyde, reaction of EC 1.1.1.283. Mer does not catalyze the reduction of methylglyoxal to lactaldehyde in the presence of reduced Fo, the precursor of cofactor F420
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