1.5.4.1: pyrimidodiazepine synthase
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For detailed information about pyrimidodiazepine synthase, go to the full flat file.
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Synonyms
More, PDA synthase
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Systematic Name
Systematic Name on EC 1.5.4.1 - pyrimidodiazepine synthase
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2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)
In the reverse direction, the reduction of 6-pyruvoyl-tetrahydropterin is accompanied by the opening of the 6-membered pyrazine ring and the formation of the 7-membered diazepine ring. The pyrimidodiazepine formed is an acetyldihydro derivative. Involved in the formation of the eye pigment drosopterin in Drosophila melanogaster.