1.5.3.4: N6-methyl-lysine oxidase

This is an abbreviated version!
For detailed information about N6-methyl-lysine oxidase, go to the full flat file.

Reaction

Synonyms

epsilon-alkyl-L-lysine:oxygen oxidoreductase, epsilon-alkyllysinase, epsilon-N-methyllysine demethylase, More, N6-methyllysine oxidase, oxidase, N6-methyllysine

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.3 With oxygen as acceptor

1.5.3.4 N6-methyl-lysine oxidase

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Results	in table
1	Activating Compound
3	AA Sequence
1	CAS Registry Number
3	Cofactor
1	Crystallization (Commentary)
1	General Stability
17	Inhibitors
6	KM Value [mM]
4	Localization
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
11	Organism
3	pH Optimum
2	pH Range
6	Purification (Commentary)
2	Reaction
4	Reaction Type
11	Reference
24	Source Tissue
7	Specific Activity [micromol/min/mg]
33	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 1.5.3.4 - N6-methyl-lysine oxidase

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2,6-dichlorophenolindophenol

ascorbic acid

moderate inhibition

Co2+

FAD

moderate inhibition

FMN

moderate inhibition

KCN

1.3 mM, about 40% inhibition

Mn2+

moderate inhibition

NADH

moderate inhibition

Ni2+

phosphate

inhibits activity in crude homogenate, but stimulates enzyme in prepared mitochondrial fraction

392428

Zn2+

2 entries

additional information

Rattus norvegicus

not inhibited by semicarbazide

392428