Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.5.3.2: N-methyl-L-amino-acid oxidase

This is an abbreviated version!
For detailed information about N-methyl-L-amino-acid oxidase, go to the full flat file.

Word Map on EC 1.5.3.2

Reaction

an N-methyl-L-amino acid
+
H2O
 +
O2
=
an L-amino acid
 +
formaldehyde
 +
H2O2

Synonyms

demethylase, N-methylamino acid oxidase, oxidase, N-methylamino acid

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.2 N-methyl-L-amino-acid oxidase

Advanced search results

Do not include text mining results
Include results (more...)
Include results (more...)
Resultsin table
1063AA Sequence
1CAS Registry Number
1Cofactor
1Inhibitors
1KM Value [mM]
1Organism
1pH Optimum
2Reaction
4Reaction Type
1Reference
1Source Tissue
9Substrates and Products (Substrate)
3Synonyms
1Systematic Name

Substrates Products

Substrates Products on EC 1.5.3.2 - N-methyl-L-amino-acid oxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
alpha-N-methyl-L-histidine + O2 + H2O
L-histidine + formaldehyde + H2O2
show the reaction diagram
-
-
-
-
?
alpha-N-methyl-L-tryptophan + O2 + H2O
L-tryptophan + formaldehyde + H2O2
show the reaction diagram
-
alpha-N-methyl-L-tryptophan is identical with L-abrine
-
?
N-methyl-L-amino acid + O2 + H2O
L-amino acid + formaldehyde + H2O2
show the reaction diagram
-
enzyme requires the presence of a free alpha-carboxyl group in the substrate molecule, substrates with aromatic or heterocyclic substituents are more readily oxidized, followed by aliphatic N-methylamino acids with long side chain, more slowly activity towards N-methyl derivatives of beta-hydroxy-amino acids and of basic and acidic amino acids with exception of histidin, very slow demethylation of phenylsarcosine
-
?
N-methyl-L-norleucine + O2 + H2O
L-norleucine + formaldehyde + H2O2
show the reaction diagram
-
-
-
?
N-methyl-L-phenylalanine + O2 + H2O
L-phenylalanine + formaldehyde + H2O2
show the reaction diagram
-
-
-
-
?
N-methyl-L-tyrosine + O2 + H2O
L-tyrosine + formaldehyde + H2O2
show the reaction diagram
-
N-methyl-DL-tyrosine is identical with surinamine
-
-
?
N-methyldihydroxyphenyl-DL-alanine + O2 + H2O
formaldehyde + dihydroxyphenyl-DL-alanine + H2O2
show the reaction diagram
-
-
-
-
?
N-methylvanillyl-L-alanine + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
more substrates, not with: N-dimethyl-L-amino acid, N-methyl-D-amino acid, L-amino acid, D-amino acid
-
-
?