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1.5.3.19: 4-methylaminobutanoate oxidase (formaldehyde-forming)

This is an abbreviated version!
For detailed information about 4-methylaminobutanoate oxidase (formaldehyde-forming), go to the full flat file.

Reaction

4-methylaminobutanoate
+
O2
+
H2O
=
4-aminobutanoate
+
formaldehyde
+
H2O2

Synonyms

gamma-N-methylaminobutanoate oxidase, gamma-N-methylaminobutyrate oxidase, mabO

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.19 4-methylaminobutanoate oxidase (formaldehyde-forming)

General Information

General Information on EC 1.5.3.19 - 4-methylaminobutanoate oxidase (formaldehyde-forming)

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
-
in nicotine breakdown, two alternative pathways for the final steps in the catabolism of 4-methylaminobutanoate could be identified. 4-Methylaminobutanoate may be demethylated to gamma-N-aminobutyrate by gamma-N-methylaminobutanoate oxidase, EC 1.5.3.19. In an alternative pathway, amine oxidase, EC 1.5.3.21, removes methylamine from 4-methylaminobutanoate with the formation of succinic semialdehyde. Kinetic analyses suggest that demethylation predominates over deamination of 4-methylaminobutanoate