1.5.3.19: 4-methylaminobutanoate oxidase (formaldehyde-forming)
This is an abbreviated version!
For detailed information about 4-methylaminobutanoate oxidase (formaldehyde-forming), go to the full flat file.
Reaction
Synonyms
gamma-N-methylaminobutanoate oxidase, gamma-N-methylaminobutyrate oxidase, mabO
ECTree
Advanced search results
General Information
General Information on EC 1.5.3.19 - 4-methylaminobutanoate oxidase (formaldehyde-forming)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
physiological function
-
in nicotine breakdown, two alternative pathways for the final steps in the catabolism of 4-methylaminobutanoate could be identified. 4-Methylaminobutanoate may be demethylated to gamma-N-aminobutyrate by gamma-N-methylaminobutanoate oxidase, EC 1.5.3.19. In an alternative pathway, amine oxidase, EC 1.5.3.21, removes methylamine from 4-methylaminobutanoate with the formation of succinic semialdehyde. Kinetic analyses suggest that demethylation predominates over deamination of 4-methylaminobutanoate