1.5.1.46: agroclavine dehydrogenase

This is an abbreviated version!
For detailed information about agroclavine dehydrogenase, go to the full flat file.

Reaction

6,8-dimethyl-6,7,8,9-tetradehydroergoline

Synonyms

agroclavine synthase, EasG

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.1 With NAD⁺ or NADP⁺ as acceptor

1.5.1.46 agroclavine dehydrogenase

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Results	in table
1	Activating Compound
4	AA Sequence
2	Cloned(Commentary)
5	Cofactor
5	Molecular Weight [Da]
4	Organism
3	Pathway
1	Purification (Commentary)
1	Reaction
3	Reference
8	Substrates and Products (Substrate)
5	Subunits
8	Synonyms
1	Systematic Name

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Reference on EC 1.5.1.46 - agroclavine dehydrogenase

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719646

Cheng, J.; Coyle, C.; Panaccione, D.; O�Connor, S.

Controlling a structural branch point in ergot alkaloid biosynthesis

J. Am. Chem. Soc.

132

12835-12837

2010

Aspergillus fumigatus

20735127

720617

Matuschek, M.; Wallwey, C.; Xie, X.; Li, S.M.

New insights into ergot alkaloid biosynthesis in Claviceps purpurea: an agroclavine synthase EasG catalyses, via a non-enzymatic adduct with reduced glutathione, the conversion of chanoclavine-I aldehyde to agroclavine

Org. Biomol. Chem.

4328-4335

2011

Claviceps purpurea, Claviceps purpurea (P0CT21)

21494745

721046

Matuschek, M.; Wallwey, C.; Wollinsky, B.; Xie, X.; Li, S.

In vitro conversion of chanoclavine-I aldehyde to the stereoisomers festuclavine and pyroclavine controlled by the second reduction step

RSC Adv.

3662-3669

2012

Claviceps purpurea