1.5.1.34: 6,7-dihydropteridine reductase
This is an abbreviated version!
For detailed information about 6,7-dihydropteridine reductase, go to the full flat file.
Word Map on EC 1.5.1.34
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1.5.1.34
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tetrahydrobiopterin
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hydroxylase
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bh4
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hyperphenylalaninemia
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neurotransmitter
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phenylketonuria
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biopterin
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pterins
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dopamine
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quinonoid
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sepiapterin
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1.6.99.7
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cyclohydrolase
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6-pyruvoyl-tetrahydropterin
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5-hydroxytryptophan
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tetrahydropterin
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dihydrobiopterin
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l-dopa
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ptp
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folinic
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nadh-specific
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homovanillic
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pterin-4a-carbinolamine
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guthrie
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6-pyruvoyl
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dihydropterins
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gtpch
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medicine
- 1.5.1.34
- tetrahydrobiopterin
- hydroxylase
- bh4
- hyperphenylalaninemia
-
neurotransmitter
- phenylketonuria
- biopterin
- pterins
- dopamine
-
quinonoid
- sepiapterin
-
1.6.99.7
-
cyclohydrolase
- 6-pyruvoyl-tetrahydropterin
- 5-hydroxytryptophan
- tetrahydropterin
- dihydrobiopterin
- l-dopa
- ptp
-
folinic
-
nadh-specific
-
homovanillic
-
pterin-4a-carbinolamine
-
guthrie
-
6-pyruvoyl
- dihydropterins
- gtpch
- medicine
Reaction
Synonyms
7,8-dihydrobiopterin reductase, BmDhpr, DHPR, dicDHPR, dihydropteridine reductase, dihydropteridine reductase (NADH), DQPR gene product, EC 1.6.99.10, EC 1.6.99.7, EcDHPR, More, NADH-dihydropteridine reductase, NADPH-dihydropteridine reductase, NADPH-specific dihydropteridine reductase, NfsB, NprA nitroreductase, PTR2, QDPR, quinoid dihydropteridine reductase, reductase, dihydropteridine (reduced nicotinamide adenine dinucleotide)
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Application on EC 1.5.1.34 - 6,7-dihydropteridine reductase
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medicine
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enzyme deficiency leads to progressive mental and physical retardation despite dietary phenylalanine restriction. Overview on genomic structure and location of natural mutations in the QDPR gene coding for enzyme
additional information
the purified recombinant enzyme from Escherichia coli is used for 5,6,7,8-tetrahydropteridine (BH4) regeneration to alleviate 7,8-dihydropteridine (BH2) inhibition of L-tyrosine hydroxylation by crude tyrosine hydroxylase (SrTH) from Streptosporangium roseum DSM 43021 as part of a combined whole-cell catalyst, and a series of tyrosine hydroxylase/sepiapterin reductase (TH/SPR) synthesis systems, overview