1.5.1.33: pteridine reductase
This is an abbreviated version!
For detailed information about pteridine reductase, go to the full flat file.
Word Map on EC 1.5.1.33
-
1.5.1.33
-
leishmania
-
dihydrofolate
-
trypanosoma
-
antileishmanial
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antifolate
-
promastigotes
-
leishmaniasis
-
trypanosomatids
-
pterins
-
donovani
-
amastigotes
-
trypanosomiasis
-
dhfr-t
-
trypanothione
-
reductase-thymidylate
-
tarentolae
-
dihydrobiopterin
-
glucantime
-
medicine
-
drug development
-
pharmacology
- 1.5.1.33
- leishmania
- dihydrofolate
- trypanosoma
-
antileishmanial
- antifolate
- promastigotes
- leishmaniasis
-
trypanosomatids
- pterins
- donovani
- amastigotes
- trypanosomiasis
-
dhfr-t
- trypanothione
-
reductase-thymidylate
- tarentolae
- dihydrobiopterin
-
glucantime
- medicine
- drug development
- pharmacology
Reaction
Synonyms
Atu1130, EC 1.1.1.253, H region methotrexate resistance protein, LaPTR1, LbPTR1, LdPTR1, LmPTR1, LpPTR1, More, NADPH-dependent short-chain dehydrogenase/reductase pteridine reductase, NADPH-dihydropteridine reductase, PruA, pteridine reductase, pteridine reductase 1, pteridine reductase I, PTR1, reductase, dihydropteridine (reduced nicotinamide adenine dinucleotide phosphate), Tb-PR, TbPTR1, tcptr1
ECTree
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Specific Activity
Specific Activity on EC 1.5.1.33 - pteridine reductase
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0.1
0.28
recombinant mutant R24G, pH 6.0, 25°C, substrate 7,8-dihydromonapterin
1.71
recombinant mutant R24A, pH 6.0, 25°C, substrate 7,8-dihydromonapterin
2.88
recombinant mutant Y161A, pH 6.0, 25°C, substrate 7,8-dihydromonapterin
4.13
recombinant mutant Y161F/Y163F, pH 6.0, 25°C, substrate 7,8-dihydromonapterin
4.77
recombinant wild-type enzyme, pH 6.0, 25°C, substrate 7,8-dihydromonapterin
5.03
recombinant wild-type enzyme, pH 6.0, 25°C, substrate 7,8-dihydroneopterin
8.84
recombinant mutant Y163F, pH 6.0, 25°C, substrate 7,8-dihydromonapterin
9.83
recombinant wild-type enzyme, pH 6.0, 25°C, substrate 7,8-dihydrobiopterin