1.4.3.4: monoamine oxidase

This is an abbreviated version!
For detailed information about monoamine oxidase, go to the full flat file.

Reaction

Synonyms

adrenaline oxidase, amine-oxygen oxidoreductase, C-MAO, EC 1.4.3.9, epinephrine oxidase, MAO, MAO A, MAO B, MAO type B, MAO-A, MAO-B, MAO-N, MAO-N-D5, MAOA, MAOB, monoamine oxidase, monoamine oxidase A, monoamine oxidase B, monoamine oxidase N, monoamine oxidase type B, monoamine oxidase-A, monoamine oxidase-B, monoamine oxidaseA, monoamine oxidases A, monoamine oxidases B, monoamine-oxidase-A, monoamine: O2-oxidoreductase, deaminated, monoamine: O2-oxidoreductase, deaminating, monoamine: O2-oxidoreductase: deaminating, monoamine:O2 oxidoreductase (deaminating), monoamine:O2 oxidoreductase, deaminating, monoamine:O2-oxidoreductase deaminating, monoaminoxidase B, More, semicarbazide-sensitive amine oxidase, serotonin deaminase, SSAO, tyraminase, tyramine oxidase, zMAO

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.3 With oxygen as acceptor

                1.4.3.4 monoamine oxidase

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Results	in table
5	Activating Compound
737	AA Sequence
64	Application
1	CAS Registry Number
102	Cloned(Commentary)
80	Cofactor
13	Crystallization (Commentary)
7579	Disease/ Diagnostics
6	Expression
21	General Information
4	General Stability
1076	IC50 Value
1596	Inhibitors
36	kcat/KM [mM/s]
570	Ki Value [mM]
323	KM Value [mM]
113	Localization
5	Metals/Ions
33	Molecular Weight [Da]
79	Natural Substrates/ Products (Substrates)
8	Organic Solvent Stability
414	Organism
2	Oxidation Stability
28	Pathway
160	PDB ID
37	pH Optimum
6	pH Range
1	pI Value
14	Posttranslational Modification
57	Protein Variants
42	Purification (Commentary)
15	Reaction
4	Reaction Type
354	Reference
248	Source Tissue
62	Specific Activity [micromol/min/mg]
7	Storage Stability
672	Substrates and Products (Substrate)
42	Subunits
693	Synonyms
1	Systematic Name
25	Temperature Optimum [°C]
1	Temperature Range [°C]
18	Temperature Stability [°C]
144	Turnover Number [1/s]

Synonyms

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Synonyms on EC 1.4.3.4 - monoamine oxidase

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

adrenaline oxidase

-

-

-

-

amine-oxygen oxidoreductase

Rattus norvegicus

-

-

725675

C-MAO

Cyprinus carpio

-

-

711781

EC 1.4.3.9

-

-

formerly

-

epinephrine oxidase

-

-

-

-

MAO

24 entries

MAO A

9 entries

MAO B

11 entries

MAO type B

Homo sapiens

P27338

-

686193

MAO-A

45 entries

MAO-B

45 entries

MAO-N

Aspergillus niger

P46882

-

686060, 764280, 764471

MAO-N-D5

Aspergillus niger

-

-

743099

MAOA

6 entries

MAOB

4 entries

monoamine oxidase

6 entries

monoamine oxidase A

42 entries

monoamine oxidase B

46 entries

monoamine oxidase N

Aspergillus niger

P46882

-

764280, 764471

monoamine oxidase type B

Homo sapiens

P27338

-

689832

monoamine oxidase-A

5 entries

monoamine oxidase-B

4 entries

monoamine oxidaseA

Homo sapiens

P21397

-

684240

monoamine oxidases A

Homo sapiens

-

-

711407, 712683, 712684

monoamine oxidases B

Homo sapiens

-

-

711407, 712683, 712684

monoamine-oxidase-A

Homo sapiens

P21397

-

689988

monoamine: O2-oxidoreductase, deaminated

Oncorhynchus keta

-

-

742990

monoamine: O2-oxidoreductase, deaminating

4 entries

monoamine: O2-oxidoreductase: deaminating

Katsuwonus pelamis

-

-

742989

monoamine:O2 oxidoreductase (deaminating)

-

-

-

-

monoamine:O2 oxidoreductase, deaminating

Todarodes pacificus

-

-

711832

monoamine:O2-oxidoreductase deaminating

Coregonus lavaretus ludoga

-

-

725620

monoaminoxidase B

Homo sapiens

P27338

-

684233

semicarbazide-sensitive amine oxidase

Rattus norvegicus

-

-

689376

serotonin deaminase

-

-

-

-

SSAO

5 entries

tyraminase

-

-

-

-

tyramine oxidase

-

-

-

-

zMAO

Danio rerio

-

-

713457

additional information

10 entries

MAO

-

-

-

-

MAO

Acipenser gueldenstaedtii

-

-

742988

MAO

Acipenser persicus

-

-

742988

MAO

Acipenser stellatus

-

-

742988

MAO

Aspergillus niger

-

-

743095

MAO

Avena sativa

-

-

723891

MAO

Coregonus lavaretus ludoga

-

-

725620

MAO

Danio rerio

-

-

705252, 724786

MAO

Danio rerio

Q6NSN2

-

703488

MAO

Danio rerio Turku

-

-

-

MAO

Homo sapiens

-

-

687158, 711899, 712051, 712076, 743640

MAO

Homo sapiens

P27338

-

684770, 688255, 711911

MAO

Huso huso

-

-

742988

MAO

Katsuwonus pelamis

-

-

742989

MAO

Lampetra fluviatilis

-

-

725622

MAO

Narcissus tazetta

-

-

724603

MAO

Neogale vison

-

-

706934

MAO

Oncorhynchus keta

-

-

742990

MAO

Pelophylax ridibundus

-

-

725619

MAO

Poecilia reticulata

Q0PGS2

-

703488

MAO

Pusa hispida ladogensis

-

-

725621

MAO

Rana temporaria

-

-

725619

MAO

Rattus norvegicus

-

-

685556, 686264, 689185, 689375, 689377, 706934, 742219

MAO

Todarodes pacificus

-

-

711832

MAO A

Bos taurus

-

-

711205

MAO A

Bos taurus

P21398

-

672601

MAO A

Homo sapiens

-

-

654840, 655288, 656047, 674612, 702238, 711205

MAO A

Homo sapiens

P21397

-

671913, 672525, 672601, 674429, 675746, 684241, 685884, 688260, 703615, 703627, 703657, 742446

MAO A

Mus musculus

-

-

711205

MAO A

Mus musculus

Q64133

-

684241, 684258

MAO A

Rattus norvegicus

-

-

711205, 724326

MAO A

Rattus norvegicus

-

isoform

706602

MAO A

Rattus norvegicus

P21396

-

675286, 706602

MAO B

Bos taurus

-

-

711205

MAO B

Bos taurus

P56560

-

672601, 674429

MAO B

Equus caballus

-

-

674429

MAO B

Homo sapiens

-

-

655288, 656047, 711205

MAO B

Homo sapiens

-

isoform

724966

MAO B

Homo sapiens

P27338

-

655583, 656469, 656857, 672532, 672601, 674429, 675746, 684241, 684263, 688260, 690114, 702238, 742446, 742919

MAO B

Mus musculus

-

-

711205

MAO B

Mus musculus

Q8BW75

-

674429

MAO B

Ovis aries

-

-

674429

MAO B

Rattus norvegicus

-

-

711205

MAO B

Rattus norvegicus

P19643

-

674429, 675286

MAO-A

Bos taurus

P21398

-

673203, 675287, 686527, 688268

MAO-A

Callithrix jacchus

-

-

686942

MAO-A

Cebus albifrons

-

-

686942

MAO-A

Colobus guereza

-

-

686942

MAO-A

Gorilla gorilla

-

-

686942

MAO-A

Homo sapiens

-

-

654463, 655721, 656361, 656957, 702900, 706679, 706847, 711164, 711355, 711407, 711446, 711464, 711912, 712579, 712683, 712684, 713198

MAO-A

Homo sapiens

P21397

-

394552, 672531, 684240, 684290, 685418, 685839, 686264, 686325, 686347, 686479, 686534, 686554, 687244, 688267, 688478, 688479, 688481, 688603, 689205, 689207, 689834, 689988, 690022, 702565, 742443, 764270, 764275, 764276, 764555, 765139, 765254

MAO-A

Homo sapiens

P27338

-

711911, 742065

MAO-A

Hylobates lar

-

-

686942

MAO-A

Macaca arctoides

-

-

686942

MAO-A

Macaca assamensis

-

-

686942

MAO-A

Macaca brunnescens

-

-

686942

MAO-A

Macaca cyclopis

-

-

686942

MAO-A

Macaca fascicularis

-

-

686942

MAO-A

Macaca fuscata

-

-

656607, 686942

MAO-A

Macaca hecki

-

-

686942

MAO-A

Macaca maura

-

-

686942

MAO-A

Macaca mulatta

-

-

686942

MAO-A

Macaca nemestrina

-

-

686942

MAO-A

Macaca nigra

-

-

686942

MAO-A

Macaca ochreata

-

-

686942

MAO-A

Macaca radiata

-

-

686942

MAO-A

Macaca silenus

-

-

686942

MAO-A

Macaca sinica

-

-

686942

MAO-A

Macaca sylvanus

-

-

686942

MAO-A

Macaca thibetana

-

-

686942

MAO-A

Macaca tonkeana

-

-

686942

MAO-A

Mandrillus sphinx

-

-

686942

MAO-A

Mesocricetus auratus

-

-

705901

MAO-A

Miopithecus talapoin

-

-

686942

MAO-A

Mus musculus

-

-

656875, 706708, 711164

MAO-A

Mus musculus

Q64133

-

690076, 701958

MAO-A

Oryctolagus cuniculus

-

-

656607, 686873

MAO-A

Pan troglodytes

Q5UL86

-

686942

MAO-A

Papio anubis

-

-

711446

MAO-A

Papio sp.

-

-

706796

MAO-A

Pongo pygmaeus

-

-

686942

MAO-A

Rattus norvegicus

-

-

655523, 656607, 656683, 657397, 711442, 712690

MAO-A

Rattus norvegicus

-

isoform

725675

MAO-A

Rattus norvegicus

P21396

-

672492, 675304, 684770, 685472, 685521, 686179, 686554, 688063, 688257, 688480, 688481, 688486, 688492, 701984, 702639, 705454, 711449, 742357, 742443

MAO-A

Rattus norvegicus

P21936

-

702632

MAO-A

Saguinus oedipus

-

-

686942

MAO-A

Saimiri sciureus

-

-

686942

MAO-A

Sus scrofa

Q6Q2J0

-

688271

MAO-A

Trachypithecus francoisi

-

-

686942

MAO-B

Bos taurus

-

-

655781

MAO-B

Bos taurus

P56560

-

673203, 675287, 686527, 688268, 688763

MAO-B

Callithrix jacchus

-

-

686942

MAO-B

Cebus albifrons

-

-

686942

MAO-B

Colobus guereza

-

-

686942

MAO-B

Gorilla gorilla

-

-

686942

MAO-B

Homo sapiens

-

-

654463, 655523, 655721, 656361, 657163, 657397, 706847, 710705, 711355, 711407, 711446, 711447, 711464, 711912, 712567, 712579, 712683, 712684, 713198, 724524

MAO-B

Homo sapiens

P27338

-

672579, 684233, 684261, 684862, 685418, 685540, 685839, 686193, 686264, 686347, 686554, 686571, 687244, 688267, 688477, 688603, 689175, 689204, 689716, 702565, 704855, 705020, 705940, 711424, 711911, 720287, 720626, 742064, 742065, 742443, 764270, 764275, 764276, 764555, 765139, 765219, 765252, 765254

MAO-B

Hylobates lar

-

-

686942

MAO-B

Macaca arctoides

-

-

686942

MAO-B

Macaca assamensis

-

-

686942

MAO-B

Macaca brunnescens

-

-

686942

MAO-B

Macaca cyclopis

-

-

686942

MAO-B

Macaca fuscata

-

-

656607, 686942

MAO-B

Macaca hecki

-

-

686942

MAO-B

Macaca maura

-

-

686942

MAO-B

Macaca mulatta

-

-

686942

MAO-B

Macaca nemestrina

-

-

686942

MAO-B

Macaca nigra

-

-

686942

MAO-B

Macaca ochreata

-

-

686942

MAO-B

Macaca radiata

-

-

686942

MAO-B

Macaca silenus

-

-

686942

MAO-B

Macaca sinica

-

-

686942

MAO-B

Macaca sylvanus

-

-

686942

MAO-B

Macaca thibetana

-

-

686942

MAO-B

Macaca tonkeana

-

-

686942

MAO-B

Mandrillus sphinx

-

-

686942

MAO-B

Mesocricetus auratus

-

-

705901

MAO-B

Miopithecus talapoin

-

-

686942

MAO-B

Mus musculus

-

-

705940

MAO-B

Mus musculus

Q8BW75

-

688763, 689236, 701958

MAO-B

Pan troglodytes

-

-

686942

MAO-B

Papio anubis

-

-

711446

MAO-B

Papio hamadryas

-

-

672531, 685517, 685535

MAO-B

Papio sp.

-

-

688763, 702669, 706796, 711437

MAO-B

Pongo pygmaeus

-

-

686942

MAO-B

Rattus norvegicus

-

-

655523, 656683, 657397, 711442, 711447, 712690

MAO-B

Rattus norvegicus

-

isoform

725675

MAO-B

Rattus norvegicus

P19643

-

672492, 675304, 685472, 685521, 685883, 686554, 688063, 688257, 688480, 688486, 688492, 701984, 702632, 702639, 705454, 742357, 742443, 765252

MAO-B

Rattus norvegicus

P19643

isoform

743126

MAO-B

Rattus norvegicus

P21396

-

684770, 711449

MAO-B

Rattus norvegicus Wistar

P19643

-

-

MAO-B

Saguinus oedipus

-

-

686942

MAO-B

Saimiri sciureus

-

-

686942

MAO-B

Trachypithecus francoisi

-

-

686942

MAOA

Homo sapiens

-

-

705925

MAOA

Homo sapiens

-

isoform

743640

MAOA

Homo sapiens

P21397

-

672530, 684305, 684306, 684308, 684810, 685879, 686478, 688543, 689711, 690172, 702228, 702297

MAOA

Rattus norvegicus

-

-

394556, 654113

MAOA

Rattus norvegicus

P21396

-

656536, 689993, 702228

MAOA

Rattus norvegicus MAO-A

-

-

-

MAOB

Homo sapiens

-

isoform

743640

MAOB

Homo sapiens

P21397

-

684304

MAOB

Homo sapiens

P27338

-

672530, 684444, 689829, 702228, 702297

MAOB

Rattus norvegicus

P19643

-

702228

monoamine oxidase

-

-

-

-

monoamine oxidase

Homo sapiens

-

-

687158

monoamine oxidase

Homo sapiens

P21397, P27338

-

684241

monoamine oxidase

Lontra canadensis

-

-

687025

monoamine oxidase

Mus musculus

Q64133

-

684241

monoamine oxidase

Rattus norvegicus

-

-

685434, 685556, 689377

monoamine oxidase A

Bos taurus

-

-

711205

monoamine oxidase A

Bos taurus

P21398

-

686527, 688268

monoamine oxidase A

Callithrix jacchus

-

-

686942

monoamine oxidase A

Cebus albifrons

-

-

686942

monoamine oxidase A

Colobus guereza

-

-

686942

monoamine oxidase A

Gallus gallus

-

-

655187

monoamine oxidase A

Gorilla gorilla

-

-

686942

monoamine oxidase A

Homo sapiens

-

-

654840, 655288, 656047, 656361, 656957, 702238, 702900, 705925, 706679, 711205, 711446, 713198

monoamine oxidase A

Homo sapiens

P21397

-

394552, 671913, 672530, 672531, 674429, 684301, 684305, 684308, 684810, 685243, 685418, 685838, 685839, 685879, 686325, 686347, 686478, 686554, 687244, 687285, 688260, 688478, 688543, 689205, 689207, 689711, 689834, 689835, 702297, 702546, 703615, 703627, 703657, 742443, 742446, 764275, 764276, 764293

monoamine oxidase A

Hylobates lar

-

-

686942

monoamine oxidase A

Macaca arctoides

-

-

686942

monoamine oxidase A

Macaca assamensis

-

-

686942

monoamine oxidase A

Macaca brunnescens

-

-

686942

monoamine oxidase A

Macaca cyclopis

-

-

686942

monoamine oxidase A

Macaca fascicularis

-

-

686942

monoamine oxidase A

Macaca fuscata

-

-

656607, 686942

monoamine oxidase A

Macaca hecki

-

-

686942

monoamine oxidase A

Macaca maura

-

-

686942

monoamine oxidase A

Macaca mulatta

-

-

686942

monoamine oxidase A

Macaca nemestrina

-

-

686942

monoamine oxidase A

Macaca nigra

-

-

686942

monoamine oxidase A

Macaca ochreata

-

-

686942

monoamine oxidase A

Macaca radiata

-

-

686942

monoamine oxidase A

Macaca silenus

-

-

686942

monoamine oxidase A

Macaca sinica

-

-

686942

monoamine oxidase A

Macaca sylvanus

-

-

686942

monoamine oxidase A

Macaca thibetana

-

-

686942

monoamine oxidase A

Macaca tonkeana

-

-

686942

monoamine oxidase A

Mandrillus sphinx

-

-

686942

monoamine oxidase A

Miopithecus talapoin

-

-

686942

monoamine oxidase A

Mus musculus

-

-

656875, 706708, 711205

monoamine oxidase A

Mus musculus

Q64133

-

684258, 686250

monoamine oxidase A

Oryctolagus cuniculus

-

-

656607, 686873

monoamine oxidase A

Pan troglodytes

Q5UL86

-

686942

monoamine oxidase A

Papio anubis

-

-

711446

monoamine oxidase A

Pongo pygmaeus

-

-

686942

monoamine oxidase A

Rattus norvegicus

-

-

654113, 656607, 656683, 657397, 711205, 712690, 724326

monoamine oxidase A

Rattus norvegicus

-

isoform

706602, 725675

monoamine oxidase A

Rattus norvegicus

P21396

-

656536, 672492, 675251, 684770, 685243, 685886, 686179, 686554, 689177, 701984, 706602, 742357, 742443

monoamine oxidase A

Saguinus oedipus

-

-

686942

monoamine oxidase A

Saimiri sciureus

-

-

686942

monoamine oxidase A

Trachypithecus francoisi

-

-

686942

monoamine oxidase B

Bos taurus

-

-

655781, 711205

monoamine oxidase B

Bos taurus

P56560

-

655781, 674429, 686527, 688268, 688763, 689177

monoamine oxidase B

Callithrix jacchus

-

-

686942

monoamine oxidase B

Cebus albifrons

-

-

686942

monoamine oxidase B

Colobus guereza

-

-

686942

monoamine oxidase B

Equus caballus

-

-

674429

monoamine oxidase B

Gallus gallus

-

-

655187

monoamine oxidase B

Gorilla gorilla

-

-

686942

monoamine oxidase B

Homo sapiens

-

-

655288, 656047, 656361, 657163, 657397, 710705, 711205, 711446, 711447, 711464, 712567, 713198, 724524

monoamine oxidase B

Homo sapiens

P21397

-

684304

monoamine oxidase B

Homo sapiens

P27338

-

655583, 656469, 656857, 672153, 672530, 672532, 674429, 684261, 684263, 684444, 684770, 684862, 685243, 685418, 685839, 686347, 686554, 686571, 687244, 688260, 688477, 689175, 689204, 689829, 702238, 702297, 702546, 705020, 705940, 711424, 742443, 742446, 742919, 764275, 764276, 764293, 765219

monoamine oxidase B

Hylobates lar

-

-

686942

monoamine oxidase B

Macaca arctoides

-

-

686942

monoamine oxidase B

Macaca assamensis

-

-

686942

monoamine oxidase B

Macaca brunnescens

-

-

686942

monoamine oxidase B

Macaca cyclopis

-

-

686942

monoamine oxidase B

Macaca fuscata

-

-

656607, 686942

monoamine oxidase B

Macaca hecki

-

-

686942

monoamine oxidase B

Macaca maura

-

-

686942

monoamine oxidase B

Macaca mulatta

-

-

686942

monoamine oxidase B

Macaca nemestrina

-

-

686942

monoamine oxidase B

Macaca nigra

-

-

686942

monoamine oxidase B

Macaca ochreata

-

-

686942

monoamine oxidase B

Macaca radiata

-

-

686942

monoamine oxidase B

Macaca silenus

-

-

686942

monoamine oxidase B

Macaca sinica

-

-

686942

monoamine oxidase B

Macaca sylvanus

-

-

686942

monoamine oxidase B

Macaca thibetana

-

-

686942

monoamine oxidase B

Macaca tonkeana

-

-

686942

monoamine oxidase B

Mandrillus sphinx

-

-

686942

monoamine oxidase B

Miopithecus talapoin

-

-

686942

monoamine oxidase B

Mus musculus

-

-

705940, 711205

monoamine oxidase B

Mus musculus

Q8BW75

-

674429, 688763

monoamine oxidase B

Ovis aries

-

-

674429

monoamine oxidase B

Pan troglodytes

-

-

686942

monoamine oxidase B

Papio anubis

-

-

711446

monoamine oxidase B

Papio hamadryas

-

-

672531, 672541, 685517, 685535

monoamine oxidase B

Papio sp.

-

-

688763, 702669, 711437

monoamine oxidase B

Pongo pygmaeus

-

-

686942

monoamine oxidase B

Rattus norvegicus

-

-

656683, 657397, 711205, 711447, 712690

monoamine oxidase B

Rattus norvegicus

-

isoform

725675

monoamine oxidase B

Rattus norvegicus

P19643

-

672492, 674429, 675251, 685243, 685886, 686554, 689177, 689876, 701984, 742357, 742443, 743126

monoamine oxidase B

Rattus norvegicus

P21396

-

684770

monoamine oxidase B

Saguinus oedipus

-

-

686942

monoamine oxidase B

Saimiri sciureus

-

-

686942

monoamine oxidase B

Trachypithecus francoisi

-

-

686942

monoamine oxidase-A

Homo sapiens

-

-

711164, 712579

monoamine oxidase-A

Homo sapiens

P21397

-

685475

monoamine oxidase-A

Homo sapiens

P27338

-

742065

monoamine oxidase-A

Mus musculus

-

-

711164

monoamine oxidase-A

Rattus norvegicus

P21396

-

675099

monoamine oxidase-B

Homo sapiens

-

-

712579

monoamine oxidase-B

Homo sapiens

P27338

-

672579, 685540, 720626, 742064, 742065, 765252

monoamine oxidase-B

Mesocricetus auratus

-

-

705901

monoamine oxidase-B

Rattus norvegicus

P19643

-

765252

monoamine: O2-oxidoreductase, deaminating

Acipenser gueldenstaedtii

-

-

742988

monoamine: O2-oxidoreductase, deaminating

Acipenser persicus

-

-

742988

monoamine: O2-oxidoreductase, deaminating

Acipenser stellatus

-

-

742988

monoamine: O2-oxidoreductase, deaminating

Huso huso

-

-

742988

SSAO

Bos taurus

-

-

689723

SSAO

Camelus bactrianus

-

-

689723

SSAO

Capra hircus

-

-

689723

SSAO

Equus caballus

-

-

689723

SSAO

Ovis aries

-

-

689723

additional information

Homo sapiens

-

isoforms differ in inhibitor sensitivity

394568

additional information

Homo sapiens

-

isoforms differ in inhibitor sensitivity

394572

additional information

Homo sapiens

-

MAO is a novel type of disulfide oxidoreductase

394553

additional information

Homo sapiens

-

MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures

394568

additional information

Homo sapiens

-

the N-terminal region of the two isoenzymes is not involved in the different specificity of the two isoenzymes for substrates and inhibitors

394582

additional information

Rattus norvegicus

-

isoforms differ in inhibitor sensitivity

394574

additional information

Rattus norvegicus

-

MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures

394562

additional information

Rattus norvegicus

-

MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures

394574

additional information

Sus scrofa

-

isoforms differ in inhibitor sensitivity

394570

additional information

Sus scrofa

-

MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures

394570