1.4.3.3: D-amino-acid oxidase
This is an abbreviated version!
For detailed information about D-amino-acid oxidase, go to the full flat file.
Word Map on EC 1.4.3.3
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1.4.3.3
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d-serine
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schizophrenia
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peroxisomal
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flavin
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n-methyl-d-aspartate
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d-alanine
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catalase
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fad
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nmda
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deamination
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benzoate
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flavoenzyme
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flavoproteins
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racemase
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variabilis
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l-amino
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neurotransmission
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d-aspartate
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gracilis
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co-agonist
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rhodotorula
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cephalosporin
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glutamatergic
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urate
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d-proline
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d-ala
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d-ser
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imino
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antipsychotic
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hypofunction
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d-methionine
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isoalloxazine
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acylase
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fad-containing
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toruloides
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rhodosporidium
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d-glutamate
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fad-dependent
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d-cysteine
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kynurenic
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sulfurtransferase
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d-valine
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synthesis
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medicine
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d-leucine
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cerium
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7-aminocephalosporanic
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d-tryptophan
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d-phenylalanine
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neuregulin
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3-mercaptopyruvate
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sarcosine
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industry
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biotechnology
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analysis
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diagnostics
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drug development
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pharmacology
- 1.4.3.3
- d-serine
-
schizophrenia
- peroxisomal
- flavin
- n-methyl-d-aspartate
- d-alanine
- catalase
- fad
- nmda
-
deamination
- benzoate
-
flavoenzyme
- flavoproteins
- racemase
- variabilis
-
l-amino
-
neurotransmission
- d-aspartate
- gracilis
-
co-agonist
- rhodotorula
- cephalosporin
-
glutamatergic
- urate
- d-proline
- d-ala
- d-ser
-
imino
-
antipsychotic
-
hypofunction
- d-methionine
- isoalloxazine
- acylase
-
fad-containing
- toruloides
- rhodosporidium
- d-glutamate
-
fad-dependent
- d-cysteine
-
kynurenic
- sulfurtransferase
- d-valine
- synthesis
- medicine
- d-leucine
- cerium
-
7-aminocephalosporanic
- d-tryptophan
- d-phenylalanine
- neuregulin
- 3-mercaptopyruvate
- sarcosine
- industry
- biotechnology
- analysis
- diagnostics
- drug development
- pharmacology
Reaction
Synonyms
chDAO, D-AAO, D-amino acid oxidase, D-amino-acid-oxidase, D-aminoacid oxidase, DAAO, DAMOX, DAO, DAO1, DaoE, hDAAO, ophio-amino-acid oxidase, oxidase, D-amino acid, PEG-DAO, pkDAAO, RgDAAO, TvDAAO, TvDAO, LH99
ECTree
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Source Tissue
Source Tissue on EC 1.4.3.3 - D-amino-acid oxidase
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DAO mRNA levels are positively correlated with age <2 years in the cerebellum and amygdala
DAO activity is significantly higher in the caput region than corpus and cauda regions of epididymis
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D-amino acid oxidase is localized in the transitional cells, which are parasensory cells located between the sensory epithelium and the dark cells
additional information
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in lower brain stem and cerebellum, as well as type-1 astrocytes from cerebral cortex and the cerebellum
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gene expression of DAAO in a post-mortem study of elderly patients with schizophrenia and non-affected controls in both hemispheres differentiating between gray and white matter, overview
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in choroid plexus epithelial cells and glial cells of rhombencephalon. Higher level of DAO expression is observed in schizophrenic choroid plexus epithelial cells than that in non-schizophrenic cases
post-mortem brain. DAOA protein but not DAOA mRNA is detected in all brain regions studied, with a significant positive correlation (controlled for age) between DAO and DAO activator protein in all of the brain regions studied except for the frontal cortex
in choroid plexus epithelial cells, glial cells of pons, medulla oblongata, and especially in Bergmann glia of cerebellum
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DAO is restricted to the lower brainstem, cerebellum and spinal cord, decreasing levels in the midbrain, the cortex and hippocampus
higher expression of DAO mRNA in the cerebellum, but lower expression of DAO protein in the cerebellum compared to the other brain regions studied. DAO mRNA levels are positively correlated with age <2 years in the cerebellum and amygdala
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rat C6 glial cell overexpressing mouse D-amino acid oxidase designated as C6/DAO
DAO activity in the kidney is decreased in female mice compared with that in male mice
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D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity
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391827, 391828, 391829, 391830, 391831, 391835, 391838, 391842, 391843, 391845, 391849, 391851, 391854, 391860, 391862, 654215, 655117, 672703, 674365, 684417, 687746, 695560, 696158, 699830, 711325, 742439, 743191, 743827, 743863
additional information
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in situ hybridization and immunohistochemic determination
additional information
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no activity in liver. D-serine occurs in the cerebral cortex, hippocampus, anterior olfactory nucleus, olfactory tubercle, and amygdale, D-serine tissue distribution, overview
additional information
in situ hybridization and immunohistochemic determination
additional information
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D-serine occurs in the cerebral cortex, hippocampus, anterior olfactory nucleus, olfactory tubercle, and amygdale, D-serine tissue distribution, overview