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1.4.3.15: D-glutamate(D-aspartate) oxidase

This is an abbreviated version!
For detailed information about D-glutamate(D-aspartate) oxidase, go to the full flat file.

Reaction

D-Aspartate
+
H2O
+
O2
=
oxaloacetate
+
NH3
+
H2O2

Synonyms

ChDASPO, D-aspartate oxidase, D-glutamic-aspartic oxidase, D-monoaminodicarboxylic acid oxidase, DDO, DDO-1

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.15 D-glutamate(D-aspartate) oxidase

Substrates Products

Substrates Products on EC 1.4.3.15 - D-glutamate(D-aspartate) oxidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-aspartate + H2O + O2
oxaloacetate + NH3 + H2O2
show the reaction diagram
-
-
-
?
D-aspartic acid + H2O + O2
oxaloacetate + NH3 + H2O2
show the reaction diagram
D-glutamate + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
the enzyme (DDO-1) efficiently and selectively degrades D-glutamate in addition to D-aspartate, even in the presence of various other amino acids
-
-
?
D-glutamic acid + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
additional information
?
-
-
DL-alpha-aminoadipic acid not deaminated, alpha-aminomalonic acid not deaminated, possible acceptors: oxygen, ferricyanide, 2,6-dichlorophenol-indophenol and methylene blue
-
-
?