1.4.3.10: putrescine oxidase

This is an abbreviated version!
For detailed information about putrescine oxidase, go to the full flat file.

Word Map on EC 1.4.3.10

1.4.3.10

diamine

polyamines

spermidine

cadaverine

micrococcus

rubens

erythropolis

1.4.3.4

analysis

precisions

electroactive

diagnostics

food industry

Reaction

Synonyms

adenine dinucleotide-containing putrescine oxidase, APUO, oxidase, putrescine, PO, PuO, PUOX, PUT oxidase, PutOx, putrescine oxidase, Re-PuO

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.3 With oxygen as acceptor

1.4.3.10 putrescine oxidase

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Results	in table
439	AA Sequence
11	Application
1	CAS Registry Number
6	Cloned(Commentary)
13	Cofactor
1	Crystallization (Commentary)
61	Inhibitors
9	kcat/KM [mM/s]
43	Ki Value [mM]
34	KM Value [mM]
1	Metals/Ions
10	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
42	Organism
1	Oxidation Stability
3	Pathway
11	PDB ID
11	pH Optimum
3	pH Range
3	pH Stability
10	Protein Variants
14	Purification (Commentary)
2	Reaction
4	Reaction Type
37	Reference
7	Source Tissue
4	Specific Activity [micromol/min/mg]
3	Storage Stability
93	Substrates and Products (Substrate)
10	Subunits
23	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
12	Temperature Stability [°C]
20	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.4.3.10 - putrescine oxidase

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(2-aminoethyl)-trimethylammonium

Rhodococcus erythropolis

B0F9F6

competitive inhibitor

684634

1,1,4,4-tetramethyl-1,4-diaminobutane

1,10-Diaminodecane

1,12-diaminododecane

1,3-diaminopropane

1,6-diaminohexane

1,7-Diaminoheptane

1,8-diaminooctane

1-aminoethanol

1-ethyl-3-(3-dimethylaminopropyl)carbodiimide

Kocuria rosea

the activity of the modified enzyme towards putrescine is 5.6% of that of the native enzyme. The modified enzyme shows activity towards monoamines such as n-butylamine, n-hexylamine and n-octylamine, which are not substrates of the native enzyme

2-Aminoethanol

3-Amino-1-propanol

4-amino-1-butanoic acid

Kocuria rosea

395447

5-amino-1-pentanoic acid

5-amino-1-pentanol

6-amino-1-hexanoic acid

6-amino-1-hexanol

8-amino-1-octanoic acid

agmatine

allylamine

Aminoethanol

Rhodococcus erythropolis

B0F9F6

competitive inhibitor

684634

aminoguanidine

Bos taurus

395442

Aminoguanidine hydrogen carbonate

ammonium

benzylamine

Butylamine

cadaverine

noncompetitive against putrescine

395438

Cd2+

Kocuria rosea

inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme

395448

Co2+

Kocuria rosea

inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme

395448

Cu2+

Kocuria rosea

inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme

cyanide

dodecylamine

ethylamine

ethylenediamine

heptylamine

Hexylamine

Hg2+

inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme

hydroxylamine

Iproniazid

methylamine

methylglyoxal bis(guanylhydrazine)dihydrochloride monohydrate

Bos taurus

395442

N,N,N',N'-tetramethyl-1,4-diaminobutane

Kocuria rosea

395447

n-butylamine

Rhodococcus erythropolis

B0F9F6

competitive inhibitor

684634

Ni2+

Kocuria rosea

inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme

PCMB

pentylamine

Phenylethylamine

Propylamine

putrescine

spermidine

competitive inhibition of putrescine oxidation

395446

spermine

Kocuria rosea

competitive inhibition of putrescine oxidation

tyramine

Zn2+

inactivation due to dissociation of FAD from the enzyme molecule and denaturation of the apoenzyme

395448

additional information

3 entries