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1.4.1.B4: carboxynorspermidine dehydrogenase

This is an abbreviated version!
For detailed information about carboxynorspermidine dehydrogenase, go to the full flat file.

Reaction

L-aspartic 4-semialdehyde
+
1,3-diaminopropane
+
NADPH
+
H+
=
carboxynorspermidine
+
NADP+
+
H2O

Synonyms

C-NSPD synthase, CANSDH, carboxynorspermidine synthase

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.B4 carboxynorspermidine dehydrogenase

General Information

General Information on EC 1.4.1.B4 - carboxynorspermidine dehydrogenase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
the enzyme is found in diverse bacterial phyla, overview. orthologues encoding carboxyspermidine dehydrogenase and carboxyspermidine decarboxylase are found clustered with an array of diverse putrescine biosynthetic genes in different bacterial genomes, consistent with a role in spermidine, rather than sym-norspermidine biosynthesis
malfunction
the CASDH gene deletion strain grows normally
physiological function