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1.4.1.7: serine 2-dehydrogenase

This is an abbreviated version!
For detailed information about serine 2-dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.7

Reaction

L-serine
+
H2O
+
NAD+
=
3-hydroxypyruvate
+
NH3
+
NADH
+
H+

Synonyms

L-serine:NAD oxidoreductase (deaminating), NAD+-dependent L-serine dehydrogenase, protein PA0743, serine dehydrogenase

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.7 serine 2-dehydrogenase

Cofactor

Cofactor on EC 1.4.1.7 - serine 2-dehydrogenase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NAD+
-
binding GLGXMG motif-1 and motif-4, the nicotinamide moiety of NAD+ is mostly buried in the interdomain cleft of the PA0743 protomer
NADH
-
specific for NADH, does not react with NADPH, strictly specific for hydroxypyruvate in presence of NADH