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1.4.1.16: diaminopimelate dehydrogenase

This is an abbreviated version!
For detailed information about diaminopimelate dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.16

Reaction

meso-2,6-diaminoheptanedioate
+
H2O
+
NADP+
=
L-2-amino-6-oxoheptanedioate
+
NH3
+
NADPH
+
H+

Synonyms

BAB07799, BF3690, DAPDH, DDH, meso-2,6-diaminopimelate dehydrogenase, meso-alpha,epsilon-diaminopimelate dehydrogenase, meso-DAPDH, meso-diaminopimelate dehydrogenase, NADP+-dependent meso-diaminopimelate dehydrogenase, Sth1425, Theth_1310

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.16 diaminopimelate dehydrogenase

KM Value

KM Value on EC 1.4.1.16 - diaminopimelate dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
46.1
2-oxo-3-methylbutanoate
mutant W121L/H227I, pH 9, 30°C
12.2
2-oxo-3-phenylpropanoate
mutant W121L/H227I, pH 9, 30°C
17.72
2-oxo-4-methylpentanoate
mutant W121L/H227I, pH 9, 30°C
33.83
2-oxo-4-phenylbutanoate
mutant W121L/H227I, pH 9, 30°C
35.12
2-oxobutanoate
mutant W121L/H227I, pH 9, 30°C
23.5
2-oxopentanoate
mutant W121L/H227I, pH 9, 30°C
36.16 - 57.04
2-oxovalerate
97.88 - 119.2
3-methyl-2-oxobutanoate
26.88 - 33.51
4-methyl-2-oxopentanoate
0.21 - 0.28
L-2-amino-6-oxopimelate
0.11 - 0.57
L-DELTA1-tetrahydrodipicolinate
-
0.11 - 16.7
meso-2,6-diaminoheptanedioate
2.5 - 6.25
meso-2,6-diaminopimelate
3.1
meso-diaminopimelate
-
-
2 - 890
NAD+
0.18
NADH
pH 8.2, 37°C
0.00083 - 0.828
NADP+
0.1 - 0.41
NADPH
12.5 - 62.5
NH3
4.2 - 39.2
NH4+
29.92 - 31.5
oxaloacetate
11 - 24.3
phenylpyruvate
7.33 - 337.6
pyruvate
additional information
additional information
-